5-HT2C Receptors in the Pathophysiology of CNS Disease
(Sprache: Englisch)
Part of Springer's "The Receptors," series, this text is the first ever overview on the research of 5-HT2c receptors. 5-HT2c receptor research has been productive for twenty-five years, but recent years have seen an extraordinary increase in both amount...
Jetzt vorbestellen
versandkostenfrei
Buch (Gebunden)
219.99 €
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenlose Rücksendung
- Ratenzahlung möglich
Produktdetails
Produktinformationen zu „5-HT2C Receptors in the Pathophysiology of CNS Disease “
Part of Springer's "The Receptors," series, this text is the first ever overview on the research of 5-HT2c receptors. 5-HT2c receptor research has been productive for twenty-five years, but recent years have seen an extraordinary increase in both amount produced and insight gained. 5-HT2c is a prominent central serotonin receptor subtype widely expressed within the central and the peripheral nervous system and is thought to play a key role in the regulation of numerous behaviors. This text covers the molecular, cellular, anatomical, biochemical and behavioral aspects of this receptor, highlighting its distinctive regulatory properties and the emerging functional significance of constitutive activity and RNA-editing in vivo. It also investigates the receptors' therapeutic potential in many diseases, treated individually in separate chapters, including depression, drug abuse, schizophrenia, eating disorders, Parkinson's disease, Prader-Willi Syndrome, Alzheimer's disease and epilepsy.
Klappentext zu „5-HT2C Receptors in the Pathophysiology of CNS Disease “
Part of Springer's "The Receptors," series, this text is the first ever overview on the research of 5-HT2c receptors. 5-HT2c receptor research has been productive for twenty-five years, but recent years have seen an extraordinary increase in both amount produced and insight gained. 5-HT2c is a prominent central serotonin receptor subtype widely expressed within the central and the peripheral nervous system and is thought to play a key role in the regulation of numerous behaviors. This text covers the molecular, cellular, anatomical, biochemical and behavioral aspects of this receptor, highlighting its distinctive regulatory properties and the emerging functional significance of constitutive activity and RNA-editing in vivo. It also investigates the receptors' therapeutic potential in many diseases, treated individually in separate chapters, including depression, drug abuse, schizophrenia, eating disorders, Parkinson's disease, Prader-Willi Syndrome, Alzheimer's disease and epilepsy.
Inhaltsverzeichnis zu „5-HT2C Receptors in the Pathophysiology of CNS Disease “
Chapter 1 The making of the 5-HT2C receptor Jose M. Palacios, Angel Pazos and Daniel HoyerChapter 2 Serotonin 5-HT2C receptors: chemical neuronatomy in the mammalian brain Guadalupe Mengod
Chapter 3 The medicinal chemistry of 5-HT2C receptor ligands Marcello Leopoldo, Enza Lacivita, Paola De Giorgio, Francesco Berardi, Roberto Perrone
Chapter 4 Insights into 5-HT2C receptor function gained from transgenic mouse models Stephen J. Bonasera
Chapter 5 Serotonin 5-HT2C receptor signal transduction Maria N. Garnovskaya and John R. Raymond
Chapter 6 Homology modeling of 5-HT2C receptors Nicolas Renault, Amaury Farce, Philippe Chavatte
Chapter 7 5-HT2C receptor dimerization Katharine Herrick-Davis and Dinah T. Farrington
Chapter 8 RNA editing of 5-HT2C receptor and neuropsychiatric diseases Kazuya Iwamoto, Miki Bundo and Tadafumi Kato
Chapter 9 Serotonergic control of adult neurogenesis: focus on 5-HT2C receptors Annie Daszuta
Chapter 10 The constitutive activity of 5-HT2C receptors as an additional modality of interaction of the serotonergic system Sylvia Navailles, Philippe De Deurwaerdère
Chapter 11 The 5-HT2C receptor subtype controls central dopaminergic systems: evidence from electrophysiological and neurochemical studies Giuseppe Di Giovanni, Ennio Esposito and Vincenzo Di Matteo
Chapter 12 The role of serotonin-2C receptors in the pathophysiology of depression Eliyahu Dremencov, Joost HA Folgering, Sandra Hogg, Laurence Tecott and Thomas I.F.H. Cremers
Chapter 13 5-HT2C receptors and suicidal behaviour Fabio Panariello, Naima Javaid and Vincenzo De Luca
Chapter 14 The 5-HT2C receptor as a target for schizophrenia Herbert Y Meltzer, Liwen Sun and Hitoshi Hashimoto
Chapter 15 Serotonin and reward-related behaviour: focus on 5-HT2C receptors Paul J. Fletcher and Guy A. Higgins
Chapter 16 Tat-3L4F: a novel peptide for treating drug addiction by disrupting interaction between PTEN and 5-HT2C receptor Amy Hu, Lintao Jia,
... mehr
Jean-Christian Maillet, Xia Zhang
Chapter 17 The role of serotonin in eating behaviour: focus on 5-HT2C receptors Jason C.G. Halford
Chapter 18 Physiological and pathophysiological aspects of 5-HT2C receptors in basal ganglia Philippe De Deurwaerdère, Laurence Mignon and Marie-Françoise Chesselet
Chapter 19 Modeling tardive dyskinesia: predictive 5-HT2C receptor antagonist treatment Richard M. Kostrzewa
Chapter 20 The role of 5-HT2A/2C receptors in sleep and waking Jaime M. Monti and Héctor Jantos
Chapter 21 Role of alternative splicing of the 5-HT2C in the Prader-Willi syndrome Shivendra Kishore and Stefan Stamm
Chapter 22 The role of 5-HT2C receptor in epilepsy Rita Jakus and Gyorgy Bagdy
Chapter 23 The role of serotonin on attentional processes and executive functioning: focus on 5-HT2C receptors Eleftheria Tsaltas and Vasileios Boulougouris
Chapter 24 5-HT2C receptors in learning López-Vázquez Miguel Ángel, Gutiérrez-Guzmán Blanca Érika, Cervantes Miguel and Olvera-Cortés María Esther
Chapter 25 The role of 5-HT2C polymorphisms in behavioural and psychological symptoms of alzheimer's disease Antonia Pritchard
Chapter 26 Ocular hypotension: involvement of serotonergic 5-HT2C receptors Najam A. Sharifer 19 Modeling tardive dyskinesia: predictive 5-HT2C receptor antagonist treatment Richard M. Kostrzewa
Chapter 20 The role of 5-HT2A/2C receptors in sleep and waking Jaime M. Monti and Héctor Jantos
Chapter 21 Role of alternative splicing of the 5-HT2C in the Prader-Willi syndrome Shivendra Kishore and Stefan Stamm
Chapter 22 The role of 5-HT2C receptor in epilepsy Rita Jakus and Gyorgy Bagdy
Chapter 23 The role of serotonin on attentional processes and executive functioning: focus
Chapter 17 The role of serotonin in eating behaviour: focus on 5-HT2C receptors Jason C.G. Halford
Chapter 18 Physiological and pathophysiological aspects of 5-HT2C receptors in basal ganglia Philippe De Deurwaerdère, Laurence Mignon and Marie-Françoise Chesselet
Chapter 19 Modeling tardive dyskinesia: predictive 5-HT2C receptor antagonist treatment Richard M. Kostrzewa
Chapter 20 The role of 5-HT2A/2C receptors in sleep and waking Jaime M. Monti and Héctor Jantos
Chapter 21 Role of alternative splicing of the 5-HT2C in the Prader-Willi syndrome Shivendra Kishore and Stefan Stamm
Chapter 22 The role of 5-HT2C receptor in epilepsy Rita Jakus and Gyorgy Bagdy
Chapter 23 The role of serotonin on attentional processes and executive functioning: focus on 5-HT2C receptors Eleftheria Tsaltas and Vasileios Boulougouris
Chapter 24 5-HT2C receptors in learning López-Vázquez Miguel Ángel, Gutiérrez-Guzmán Blanca Érika, Cervantes Miguel and Olvera-Cortés María Esther
Chapter 25 The role of 5-HT2C polymorphisms in behavioural and psychological symptoms of alzheimer's disease Antonia Pritchard
Chapter 26 Ocular hypotension: involvement of serotonergic 5-HT2C receptors Najam A. Sharifer 19 Modeling tardive dyskinesia: predictive 5-HT2C receptor antagonist treatment Richard M. Kostrzewa
Chapter 20 The role of 5-HT2A/2C receptors in sleep and waking Jaime M. Monti and Héctor Jantos
Chapter 21 Role of alternative splicing of the 5-HT2C in the Prader-Willi syndrome Shivendra Kishore and Stefan Stamm
Chapter 22 The role of 5-HT2C receptor in epilepsy Rita Jakus and Gyorgy Bagdy
Chapter 23 The role of serotonin on attentional processes and executive functioning: focus
... weniger
Bibliographische Angaben
- 2010, XII, 560 Seiten, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Giuseppe Di Giovanni, Ennio Esposito, Vincenzo Di Matteo
- Verlag: Springer, Berlin
- ISBN-10: 1607619407
- ISBN-13: 9781607619406
- Erscheinungsdatum: 01.12.2010
Sprache:
Englisch
Rezension zu „5-HT2C Receptors in the Pathophysiology of CNS Disease “
From the reviews: "The book is well presented with good use of diagrams ! . There is a good mix of international authors with acknowledged leaders in the field being responsible for some key chapters. ! In summary this is a useful book describing the properties of a receptor that may well turn out to be a therapeutically important drug target with selective ligands already being evaluated in phase II trials for control of appetite." (R. G. Hill, British Journal of Clinical Pharmacology, May, 2011)
Pressezitat
From the reviews:"The book is well presented with good use of diagrams ... . There is a good mix of international authors with acknowledged leaders in the field being responsible for some key chapters. ... In summary this is a useful book describing the properties of a receptor that may well turn out to be a therapeutically important drug target with selective ligands already being evaluated in phase II trials for control of appetite." (R. G. Hill, British Journal of Clinical Pharmacology, May, 2011)
Kommentar zu "5-HT2C Receptors in the Pathophysiology of CNS Disease"
Schreiben Sie einen Kommentar zu "5-HT2C Receptors in the Pathophysiology of CNS Disease".
Kommentar verfassen