Advancements of Mass Spectrometry in Biomedical Research

Mass Spectrometry for Proteomics-based Investigation.- MALDI profiling and applications in medicine.- Applications of Matrix-Assisted Laser Desorption Ionization In-Source Decay Mass Spectrometry.- Proteome imaging: from classic to modern mass spectrometry-based molecular histology.- Mass Spectrometry-Based Tissue Imaging of Small Molecules.- Sequencing Proteins from Bottom to Top: Combining Techniques for Full Sequence Analysis of Glucokinase.- Proteomics and non-proteomics approaches to study stable and transient protein-protein interactions.- Contribution of Mass spectrometry-based Proteomics to Discoveries in Developmental Biology.- Profiling optimal conditions for capturing EDEM proteins complexes in melanoma using mass spectrometry.- The Methods employed in Mass Spectrometric Analysis of Posttranslational Modifications (PTMs) and Protein-Protein Interactions (PPIs).- Identification of post-translational modifications (PTMs) of proteins by mass spectrometry.- Sequence Variant and Post-translational Modification Analysis During Cell Line Selection via High-throughput Peptide Mapping.- Selective derivatization of hexahistidine-tagged recombinant proteins.- Investigation of Antibody-Drug Conjugates by Mass Spectrometry.- Mass Spectrometry- and Computational Structural Biology-Based Investigation of Proteins and Peptides.- Strategies for Membrane Protein Analysis by Mass Spectrometry.- The Potential for Ion Mobility in Pharmaceutical and Clinical Analyses.- Application of Ion Mobility Mass Spectrometry in Lipidomics.- Mass Spectrometry in Advancement of Redox Precision Medicine.- Applications for mass spectrometry in the study of ion channel structure and function.- Immuno - affinity Mass Spectrometry: A Novel Approaches with Biomedical Relevance.- Developing well-annotated species-specific protein databases using comparative proteogenomics.- Stoichiometry of heavy metal binding to peptides involved in Alzheimer's disease: mass spectrometric evidence.- Role of mass

Dr. Costel C. Darie started his biomedical career as a nurse at the Murgeni Hospital, Romania. He received his BS and MS in biochemistry at the Alexandru Ioan Cuza University from Iasi, Romania, and performed research under Dr. Vlad Artenie. He continued his Ph.D. studies with Dr. Wolfgang Haehnel at the Albert-Ludwigs Universitaet, Freiburg, Germany, after which he worked in the labs of Drs. Paul M. Wassarman & Micsunica Platica (Mount Sinai School of Medicine) and Thomas A. Neubert (New York University Medical Center). He currently is an Associate Professor of Chemistry and Biomolecular Science at Clarkson University, where he is the lead of the Biochemistry and Proteomics Group.



Dr. Alisa Woods received her BS in psychology from the State University of New York (SUNY) at Plattsburgh and her PhD in biology from the University of California, Irvine, with Dr. Christine Gall. She continued with post-doctoral training at the University of Freiburg, Germany, with Dr. Michael Frotscher and completed a Master's degree in Mental Health Counseling at the University of Massachusetts, Boston. She is currently a Research Associate Professor of Chemistry and Biomolecular Science at Clarkson University, where she works in the Laboratory for Biochemistry and Proteomics.