Applications of co-ordination compounds of Schiff's Bases

Schiff bases are the compounds carrying imine or azomethine (-C=N-) functional group. These are the condensation products of primary amines with carbonyl compounds and were first reported by Hugo Schiff . Schiff bases form an important class of the most widely used organic compounds and have a wide variety of applications in many fields including analytical, biological, and inorganic chemistry. Schiff bases have gained importance in medicinal and pharmaceutical fields due to a broad spectrum of biological activities like anti-inflammatory , analgesic , antimicrobial , anticonvulsant , antitubercular , anticancer , antioxidant , anthelmintic , and so forth. The nitrogen atom of azomethine may be involved in the formation of a hydrogen bond with the active centers of cell constituents and interferes in normal cell processes . Apart from biological activities, Schiff bases are also used as catalysts, intermediates in organic synthesis, dyes, pigments, polymer stabilizers , and corrosion inhibitors . Studies enlightened that metal complexes show greater biological activity than free organic compounds . Augmentation of biological activity was reported by implementation of transition met