Applied Biocatalysis

FERMENTATION & DOWNSTREAM PROCESSING TECHNOLOGIESProcess development tools for fermentations under extreme conditions (ProTool)Development of fully automated integrated bioprocesses in an industrial compatible pilot plant for the production of heterologous enzymes in yeastApplication of tailor made porous adsorbents in enzymatic processesIn-situ video microscopy for investigation and optimization of protein crystallization in downstream processingInnovative plasma technology for enzyme immobilizationNew membrane adsorber technology for downstream processing in enzyme production BIOCATALYSIS & BIOTECHNOLOGICAL PRODUCTION PROZESSESBiocatalysis in high viscous mediaCOMPASITES: Computer assisted analysis of active centers in proteinsKongeneric lipases with improved catalytic activity and substrate accessibilityBiocatalytic exploitation of flavonoidsNew Bacillus expression systemsFirst SeSaM-mutagenesis kit for evolutionary biocatalyst designDevelopment of a probiotic preserving agent for industrial applicationsDevelopment of a biotechnological production process for non-natural cyclopeptides - BioPEPBiocatalytic exploitation of flavor enhancing aroma compoundsSTABLE ENZYMESEnzymatic oxidation systems food and technical applicationsPreparation of new perhydrolases: Simultaneous enhancement of specific activity of perhydrolases and reduction of hydrolysis activityNucleases and proteases exhibiting improved properties for molecular preanalyticsStable enzymes for the conversion of high value and uncommon substrates

Dr. Lutz Hilterhaus carried out his studies of chemistry at the University Münster before moving to Hamburg. Having obtained his PhD from the Hamburg University of Technology (TUHH) in the working group of Prof. Liese in 2008, he spent one year with Prof. Bornscheuer at the University Greifswald before taking up the possibility to start as a Junior Group Leader at the Institute of Technical Biocatalysis at the TUHH. Dr. Lutz Hilterhaus finalized his habilitation in 2016 and has authored over 30 scientific publications and has received the "Karl-Heinz-Ditze Preis für besondere Leistungen in den Ingenieurwissenschaften" in 2008.Dr. Andreas Liese is Professor at the Hamburg University of Technology, where he is head of the Institute of Technical Biocatalysis. He studied chemistry at the University of Bonn, Germany, and carried out his doctoral research at the Research Center Jülich, Germany. From 1998 to 2003 he was head of the Enzyme Group within the Institute of Biotechnology II (Prof. Dr. C. Wandrey), Research Center Jülich. During a sabbatical in 2000 at Pfizer Global Research & Development, San Diego, USA, he there initiated a R&D group on biocatalysis. From 2003 to 2004 he worked as associate professor at the University of Münster. In 2003 Liese received the Award of Up-and-Coming Teacher in Higher Education in the field of biotechnology (DECHEMA, Germany). Since 2014 he is elected member of the steering committee of the DECHEMA e.V. Dr. Ulrich Kettling is Global Director and Head of Market Segment Industrial Enzymes at Clariant. Before he was Head of Biotechnology R&D and Global Director Biotechnology and Biorefinery at Clariant and Süd-Chemie. Before joining Süd-Chemie, Dr. Kettling was co-founder and Chief Scientific Officer of Direvo Biotech AG. Dr. Kettling graduated in Biotechnology at the Technical University Braunschweig and obtained his PhD at the Max Planck Institute for Biophysical Chemistry in Göttingen.Dr. Garabed Antranikian is Professor