Association Analysis for Big Data Related to Rheumatoid Arthritis
Genetic Association Study for Egyptian Population and GWAS for NARAC dataset
(Sprache: Englisch)
Genetics of autoimmune diseases represent a growing domain with surpassing biomarker results with rapid progress. Rheumatoid arthritis (RA) is an autoimmune disease which has a significant socio-economic impact. The exact cause of RA is unknown, but it is...
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Genetics of autoimmune diseases represent a growing domain with surpassing biomarker results with rapid progress. Rheumatoid arthritis (RA) is an autoimmune disease which has a significant socio-economic impact. The exact cause of RA is unknown, but it is thought to have both a genetic and an environmental bases. This thesis is concerned with the methods of identifying the genetic biomarkers of RA. Most of the researchers in the field of identifying RA biomarkers use single nucleotide polymorphism (SNP) approaches to express the significance of their results. Although, haplotype block methods are expected to play a complementary role in the future of that field. The used datasets belong to Egyptian population and North American population. Selection of the method used for the association discovery has a large impact on the resulted biomarkers. Finally, individual SNP approach and haplotype block methods should be applied side by side to discover valuable RA biomarkers.
Autoren-Porträt von Mohamed N. Saad
Saad, Mohamed N.Mohamed N. Saad received M.S. in Biomedical Image Processing and Ph.D. in Bioinformatics, all from Systems and Biomedical Engineering Department, Cairo University, Giza, Egypt, in 2011 and 2017 respectively. Currently, he is an Assistant Professor in the Biomedical Engineering Department, Minia University, since February 2017.
Bibliographische Angaben
- Autor: Mohamed N. Saad
- 2019, 120 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6139445116
- ISBN-13: 9786139445110
Sprache:
Englisch
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