B Cells in Immunity and Tolerance
(Sprache: Englisch)
This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development,...
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Klappentext zu „B Cells in Immunity and Tolerance “
This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.Inhaltsverzeichnis zu „B Cells in Immunity and Tolerance “
B cell development and maturation.- B cell receptor signalling.- Involvement of reactive oxygen species (ROS) in BCR signaling as a second messenger.- Germinal center reaction.- Memory B cells in local and systemic sites.- Regulation of plasma cell differentiation.- Regulation of humoral immune responses and B cell tolerance by the IgM Fc receptor.- Regulatory B cells.- Diversified IgA-bacteria interaction in gut homeostasis.- Primary antibody deficiencies.- B cell-mediated autoimmune diseases.- B cell lymphomas.
Autoren-Porträt
Dr. Ji-Yang Wang is a professor at Department of Immunology, School of Basic Medical Sciences, Fudan University, China. He was recruited to the 1000Talents Program of Shanghai in 2013. Prof. Wang's research focuses on B cell development, activation and differentiation, and B cell-related diseases. He has published more than 100 articles on international journals in these fields.Bibliographische Angaben
- 2021, 1st ed. 2020, XII, 181 Seiten, 30 farbige Abbildungen, Maße: 17,8 x 25,4 cm, Kartoniert (TB), Englisch
- Herausgegeben: Ji-Yang Wang
- Verlag: Springer, Berlin
- ISBN-10: 9811535345
- ISBN-13: 9789811535345
Sprache:
Englisch
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