Basic Immunology

1 Introduction to the Immune System      Nomenclature, General Properties, and Components 2 Innate Immunity      The Early Defense Against Infections 3 Antigen Capture and Presentation to Lymphocytes      What Lymphocytes See 4 Antigen Recognition in the Adaptive Immune System      Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires 5 T Cell¿Mediated Immunity      Activation of T Lymphocytes 6 Effector Mechanisms of T Cell¿Mediated Immunity      Functions of T Cells in Host Defense 7 Humoral Immune Responses      Activation of B Lymphocytes and Production of Antibodies 8 Effector Mechanisms of Humoral Immunity      Elimination of Extracellular Microbes and Toxins 9 Immunological Tolerance and Autoimmunity      Self-Nonself Discrimination in the Immune System and Its Failure 10 Immune Responses Against Tumors and Transplants      Immunity to Noninfectious Transformed and Foreign Cells 11 Hypersensitivity      Disorders Caused by Immune Responses 12 Congenital and Acquired Immunodeficiencies      Diseases Caused by Defective Immunity Selected Readings Appendix I Glossary Appendix II Cytokines Appendix III Principal Features of Selected CD Molecules APPENDIX IV Clinical Cases

Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California

"This well-done revision of a book on basic and relevant concepts of immunology integrates current developments in the field with clinical implications."

-Vincent K Tsiagbe, MS, Ph.D. (Rutgers University School of Dental Medicine) Doody's Score: 99-5 Stars!