Chondrogenesis Of Co-Cultured Human Adipose-Derived Stem Cells
(Sprache: Englisch)
Articular cartilage is known to have a deficient capability for tissue regeneration due to lack of vasculature. Cartilage regeneration remains challenging despite the extensive research for the past decade. Cell-based therapies are the most promising...
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Articular cartilage is known to have a deficient capability for tissue regeneration due to lack of vasculature. Cartilage regeneration remains challenging despite the extensive research for the past decade. Cell-based therapies are the most promising approach among all cartilaginous treatment for clinical application. However, cell sourcing, culture-expansion, and chondrogenic differentiation remains a challenge in cell-based tissue engineering. Previous studies have shown co-cultured in alginate constructs play a pivotal role in cell cross-talk for successful cartilaginous regeneration. Given that multipotent human adipose-derived stem cells (ADSCs) have therapeutic potential for cartilage defect; the cell-cell interactions between ADSCs and human nasal chondroctyes (NCs) for promoting chondrogenesis in a three dimensional culture environment of alginate hydrogel was investigated.
Bibliographische Angaben
- Autor: Ewa Choy Yee Wa
- 2017, 200 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6202198370
- ISBN-13: 9786202198370
Sprache:
Englisch
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