Coarse-Grained Modelling of DNA and DNA Self-Assembly
(Sprache: Englisch)
This book presents and demonstrates a coarse-grained model of DNA, simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker - it represents the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
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This book presents and demonstrates a coarse-grained model of DNA, simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker - it represents the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
Klappentext zu „Coarse-Grained Modelling of DNA and DNA Self-Assembly “
This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker - the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
Inhaltsverzeichnis zu „Coarse-Grained Modelling of DNA and DNA Self-Assembly “
A Novel DNA Model.- Methods.- Finite Size Effects.- Structural and Mechanical Properties of Model DNA.- Thermodynamic Properties of Model DNA.- Modelling DNA Tweezers.- Modelling a DNA Walker.
Bibliographische Angaben
- Autor: Thomas E. Ouldridge
- 2014, 2012, XII, 176 Seiten, Maße: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Verlag: Springer, Berlin
- ISBN-10: 3642436528
- ISBN-13: 9783642436529
Sprache:
Englisch
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