Diabetes and Kidney Disease

Background-History Part I: Natural Course, Pathogenesis, Morphology and Genetics 1. Diabetic Nephropathy-Scope of the problem (Epidemiology, US, Japan, Europe, Obesity (Metabolic Syndrome) Geriatrics2. Natural Course (Stages/Evidence Based Discussion)3. Pathogenesis: Biochemical and functional alterations involving the GBM and mesangium 4. Pathogenesis: Hemodynamic alterations/renin angiotensin system5. Renal structural damage in type 1 and type 2 DM6. Diabetes in children and adolescents7. Genetic markers and predictors of DN Part II: Clinical Presentation and Associated Disorders 8. Screening and early diagnosis (E. Cohen - Milwaukee)9. Differential diagnosis of proteinuria in DM (A. Reddi, NJ Med Sch)10. Hypertension in DM11. Cardiovascular Disease (L. Hamm, Tulane)12. Lipid disorders13. Eye complications in DN (Z. Karcioglu, U. Virginia)14. Pregnancy and DN (K. Krane-Tulane)15. Transplantation: Kidney, Kidney-Pancreas (R. Zhang) Part III: Treatment and Prognosis 16. Glycemic control17. BP control in hypertensive diabetics with proteinuria18. Early antihypertensive treatment in early stages of DN19. Lifestyle modifications20. Novel treatments (stem cells, islet cell transplants, gene transfer, etc.)

EDGAR V. LERMA, MD, FACP, FASN, FAHA, FASH, FNLA, FNKF Clinical Associate Professor of Medicine Section of Nephrology Department of Medicine University of Illinois at Chicago College of Medicine/ Associates in Nephrology, S.C.