Formulation of Film Coated Tablets of Norfloxacin and Tinidazole
(Sprache: Englisch)
The aim of the present study was development and optimization of an efficacious, pharmaco-economical, palatable and marketable film coated tablet formulation of Norfloxacin-Tinidazole. Bitter taste of both drugs reduces the patient compliance & hence...
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The aim of the present study was development and optimization of an efficacious, pharmaco-economical, palatable and marketable film coated tablet formulation of Norfloxacin-Tinidazole. Bitter taste of both drugs reduces the patient compliance & hence marketability. However it has been shown that film coating technology economical & useful in masking the taste. The core tablets with maximum hardness & minimum disintegration time were selected for film coating. (F-1 & F-07) The optimized formulation F-07 showed hardness, friability, disintegration time and drug release in range 9 kg/cm2, 0.17±0.02%, 27.40±2.1 sec. & 100% release in 30 min. respectively. For all tablet formulation drug release at the end of 30 min was found in the range of 52.78±0.09 to 100.07±0.5 % and from the obtained results, F-07 was selected as an optimized formulation for designing palatable tablet. Therefore it can be concluded that the present work discusses in depth the development and optimization of an efficacious, pharmaco-economical, palatable and marketable tablet formulation of Norfloxacin and Tinidazole.
Autoren-Porträt von Anilkumar Shinde, Harinath More
Shinde, AnilkumarDr. Anilkumar J. Shinde, M.Pharm Ph.D (Pharmacy) from Shivaji University, Kolhapur. He has nineteen years experience in marketing, teaching & researching. Presently he is working as Associate Professor in Pharmaceutics Department at Bharati Vidyapeeth College of Pharmacy, Kolhapur. He has 55 research papers, one International Nigerian patent grant.
Bibliographische Angaben
- Autoren: Anilkumar Shinde , Harinath More
- 2018, 96 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6139977363
- ISBN-13: 9786139977369
Sprache:
Englisch
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