Fundamentals of Nuclear Medicine Dosimetry

Uses of Dosimetry Information in Nuclear Medicine.- Diagnostic vs. Therapeutic Applications.- Model-Based vs. Patient-Based Approaches.- Practical Dosimetry: Balancing Benefits and Risks.- Clinical Utility: Interface of pPtient, Physician, and Physicist. Fundamental Concepts: Calculating Radiation Dose.- Dosimetry Quantities and Units.- Dosimetry Systems. Models and Resources for Internal Dose Calculations.- Standardized Models for Dosimetry.- Input Data for Dose Calculations.- Standard Dose Estimates for Radiopharmaceuticals.- Modifications to the Standard Models.- The Pregnant Patient.- The Breastfeeding Patient. Steps in Dose Calculations.- Choice and Application of Standardized Models.- Internal Dose Calculations.- Image Quantification: Human Data.- Kinetic Analysis.- Dose Calculations.- Teaching Examples.- Image-Based, Patient-Individualized Dosimetry. Case Studies.- Development of New Diagnostic Radiopharmaceuticals.- Development of Radiopharmaceuticals for Therapy.- The Pregnant Patient. Biological Effects of Radiation.- Basic Principles.- Mechanisms of Radiation Damage to Biological Systems.- Observed Biological Effects in Humans.- Cancer.- Cell Survival Studies.- Related Biological Effectiveness.- New Evidence: and Some Confusion!.- Use of Radiation Dosimetry in Patient Therapy Treatment Planning. Regulatory Aspects of Dose Calculations.- The Philosophy of Radiation Protection.- Scientific Advisory Bodies.- Regulatory Bodies.

Michael Stabin received a PhD in nuclear engineering (health physics emphasis) from the University of Tennessee in 1996 and a Master of Engineering and bachelor's degree from the University of Florida in 1983 and 1981. He worked for 15 years (1983 to 1998) at the Radiation Internal Dose Information Center in Oak Ridge, Tennessee, held a visiting professor position from 1998 to 2000 in Recife, Brazil, and currently works as an assistant professor at Vanderbilt University in Nashville, Tennessee. He serves on the editorial staffs of the Health Physics Journal, the Journal of Nuclear Medicine, and the Journal of Cancer Biotherapy and Radiopharmaceuticals. He is the author of numerous research articles and textbook chapters regarding radiation dose models and calculations, particularly in the area of nuclear medicine.

From the reviews:"This comprehensive presentation ... covers fundamental concepts of nuclear medicine dosimetry including standardized models, methods of calculation, and software applications. ... The pocket-sized dimensions of the book make it easy to carry and consult frequently in everyday situations. The extensive references and tabulated data also make it a good study tool. ... This is a comprehensive, well documented, and well thought out practical approach ... in nuclear medicine. ... highly recommended for medical physicists, physicians, and residents practicing in the field of nuclear medicine." (Dimitris N. Mihailidis, Doody's Review Service, October, 2008)