Lynch, M: Genetics and Analysis of Quantitative Traits

I. FOUNDATIONS OF QUANTITATIVE GENETICS.- An Overview of Quantitative Genetics.- Properties of Distributions.- Covariance, Regression, and Correlation.- Properties of Single Loci.- Components of Genetic Variation for Multilocus Traits.- Sources of Environmental Variation.- Resemblance between Relatives.- Introduction of Matrix Algebra and Linear Models.- Analysis of Line Crosses.- Inbreeding Depression.- Matters of Scale.- II. Quantitative Trait Loci.- Polygenes and Polygenic Mutation.- Detecting Major Genes.- Principles of Marker-Based Analysis.- Mapping and Characterizing QTLs: Inbredline Crosses.- Mapping and Characterizing QTLs: Outbred Populations.- III. Estimation Procedures.- Parent-Offspring Regression.- Sib Analysis.- Twins and Clones.- Cross-Classified Designs.- Correlations between Characters.- Genotype x Environment Interaction.- Maternal Effects Sex Linkage and Sexual Dimorphism.- Threshold Characters.- Estimation of Breeding Values.- Variance-Component Estimation with Complex Pedigrees.- Appendices.- Expectations, Variances and Covariances of Compound Variables.- Path Analysis.- Further Topics in Matrix Algebra and Linear Models.- Maximum Likelihood Estimation and Likelihood-Ratio Tests.- Computing the Power of Statistical Tests.- Literature Cited.- Author Index.- Organism and Trait Index.- Subject Index.

Michael Lynch is Distinguished Professor of Biology at Indiana University.Bruce Walsh is a Professor in the Department of Ecology and Evolutionary Biology at the University of Arizona.