Histiocytic Disorders
(Sprache: Englisch)
This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to...
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This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses.Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.
Inhaltsverzeichnis zu „Histiocytic Disorders “
Section I Pathology of Histiocytic DisordersChapter 1 Pathology of Histiocytic Disorders and Neoplasms and Related DisordersJennifer Picarsic, Ronald Jaffe
Section II : Langerhans Cell Histiocytosis (LCH)
Chapter 2 Biology and Genomics of LCH and Related DisordersBarrett J. Rollins
Chapter 3 Epidemiology and Clinical Manifestations of Langerhans Cell Histiocytosis in ChildrenEtai Adam, Rima Jubran, Sheila Weitzman
Chapter 4 Central Nervous System Langerhans Cell HistiocytosisMilen Minkov, Jennifer Picarsic, Karoly Lakatos
Chapter 5 First-line Treatment of Pediatric Langerhans Cell HistiocytosisCarlos Rodriguez-Galindo, Cor van den Bos
Chapter 6 Treatment of Relapsed and Refractory Langerhans Cell Histiocytosis in ChildrenOussama Abla, Carlos Rodriguez-Galindo, Paul Veys
Chapter 7 Adult Langerhans Cell HistiocytosisMichael Girschikofsky, Abdellatif Tazi
Chapter 8 Late Effects of Langerhans Cell Histiocytosis and the Association of LCH with Malignancy Vasanta Nanduri, Lilibeth R. Torno, Riccardo Haupt
Section III : Hemophagocytic Lymphohistiocytosis (HLH)
Chapter 9 Classification, Clinical Manifestations and Diagnostics of HLHJana Pachlopnik Schmid, Benjamin Volkmer, Stephan Ehl
Chapter 10 CNS involvement in HLH (CNS-HLH)AnnaCarin Horne, Karin Beutel
Chapter 11 Genetics and Pathogenesis of Haemophagocytic LymphohistiocytosisGeneviève de Saint Basile1, Despina Moshous, Alain Fischer
Chapter 12 Hemophagocytic Lymphohistiocytosis Associated with Malignancies and with Epstein Barr VirusChapter 13 Macrophage Activation Syndrome in Rheumatic Diseases (MAS-HLH)Alexei A. Grom, AnnaCarin Horne, Fabrizio De Benedetti
Chapter 14 Treatment of Newly Diagnosed HLH and Refractory Disease Jan-Inge Henter, Rebecca A Marsh, Tatiana von Bahr Greenwood
Chapter 15 Hematopoietic Cell Transplantation and Novel Therapies in Hemophagocytic LymphohistiocytosisK. Scott Baker, Michael B. Jordan
Chapter 16 HLH in AdultsPaul La Rosée, Rafal Machowicz
Section IV Rare Histiocytic
... mehr
Disorders: Non-Langerhans Cell Histocytosis
Chapter 17 Juvenile Xanthogranuloma and Related Non-LCH DisordersFrancesco Ceppi, Oussama Abla
Chapter 18 Erdheim-Chester Disease Eli L. Diamond, Benjamin H. Durham
Chapter 19 Rosai-Dorfman DiseaseOussama Abla, Jennifer Picarsic
Chapter 20 Malignant HistiocytosesEric Jacobsen, Oussama Abla, Johannes Visser
Chapter 17 Juvenile Xanthogranuloma and Related Non-LCH DisordersFrancesco Ceppi, Oussama Abla
Chapter 18 Erdheim-Chester Disease Eli L. Diamond, Benjamin H. Durham
Chapter 19 Rosai-Dorfman DiseaseOussama Abla, Jennifer Picarsic
Chapter 20 Malignant HistiocytosesEric Jacobsen, Oussama Abla, Johannes Visser
... weniger
Autoren-Porträt
Oussama Abla, MDChair, Rare Histiocytoses Steering Committee- Histiocyte Society, Associate Professor of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, CanadaGritta Janka, MD, PhDChair, HLH Steering Committee, Histiocyte Society, Professor emeritus of Pediatrics, University Medical Center Hamburg Eppendorf, Pediatric Hematology and Oncology, Hamburg, Germany
Bibliographische Angaben
- 2018, Softcover reprint of the original 1st ed. 2018, XII, 392 Seiten, 74 farbige Abbildungen, Maße: 17,9 x 25,2 cm, Kartoniert (TB), Englisch
- Herausgegeben: Oussama Abla, Gritta Janka
- Verlag: Springer, Berlin
- ISBN-10: 3319866672
- ISBN-13: 9783319866673
Sprache:
Englisch
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