Impact of EGFR Overexpression on Oral Cancer
Immunohistochemical overexpression of EGFR and its' correlation with patient survival in oral squamous cell carcinoma
(Sprache: Englisch)
Pakistan suffers from a very high prevalence of oral cancer. The city of Karachi has been reported to have one of the highest incidences of Oral Squamous Cell Carcinoma (OSCC) worldwide. To tackle this malignancy, new molecular markers have to be identified...
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Pakistan suffers from a very high prevalence of oral cancer. The city of Karachi has been reported to have one of the highest incidences of Oral Squamous Cell Carcinoma (OSCC) worldwide. To tackle this malignancy, new molecular markers have to be identified which can serve as targets for molecular therapy and also help clinicians predict patient prognosis with more accuracy. The Epidermal Growth Factor Receptor (EGFR) has been studied in detail for its role in various malignancies. EGFR is of special interest to researchers since it can be targeted through enzyme inhibitors or monoclonal antibodies. We investigated if EGFR was expressed above normal levels in OSCC patients of Pakistan and whether this overexpression was linked to patient overall and disease free survival. It is hoped that this book would help others pursing this line of research and provide a basis for developing better treatment protocols for OSCC patients.
Autoren-Porträt von Yumna Mirza, Syed Muhammad Adnan Ali
Mirza, YumnaYumna Mirza graduated with a Bachelors and a Masters in Biosciences from SZABIST, Karachi. She is currently a Research Instructor at The Aga Khan University, Karachi and actively investigates the role of various molecules in surgical oncology.
Bibliographische Angaben
- Autoren: Yumna Mirza , Syed Muhammad Adnan Ali
- 2020, 112 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6202075953
- ISBN-13: 9786202075954
Sprache:
Englisch
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