Induction Chemotherapy

Introduction: Overview, History, Terminology and Early Clinical Experience.- The Principle of Dose-Response in Antineoplastic Drug Delivery.- Drug Removal Systems and Induction Chemotherapy.- Cryotherapy.- Local and Regional Hyperthermia.- The Role of Hypoxia and Hyperthermia in Chemotherapy.- Induction Chemotherapy in Head and Neck Cancers.- Isolated Thoracic Perfusion with Carotid Artery Infusion for Advanced and Chemoresistant Tumors of the Parotid Gland.- Induction Chemotherapy For Breast Cancer.- Patients with Locally Advanced Breast Cancer receiving  Intra-Arterial Induction Chemotherapy: report of a Phase II Clinical Study.- Regional Chemotherapy with Thoracic Wall Recurrence and Metastasized Breast Cancer.- Cytoreductive Surgery and "Hyperthermic Intraperitoneal Chemotherapy-HIPEC.- Induction Bidirectional Chemotherapy for Gastric Cancer with Peritoneal Dissemination.- Esophageal Cancer.- Gastric Cancer.- Systemic and Regional Chemotherapy for Advanced and MetastasizedPancreatic Cancer.- Interventional Radiological Procedures for Port-Catheter Implantation.- Induction chemotherapy for hepatocellular carcinoma.- Transarterial Treatment of Primary and Secondary Liver Tumors.- Pelvic Perfusion for Rectal Cancer.- Isolated Pelvic Perfusion with Chemofiltration for Pelvic Malignancies - Anal, Cervical and Bladder Cancer.- Penile cancer treated by intra-arterial infusion chemotherapy.- Systemic Induction Chemotherapy for Advanced Stage Epithelial Ovarian Cancer.- Regional Chemotherapy in Recurrent Platinum-Refractory Ovarian Cancer.- Isolated Limb Perfusion for Melanoma.- Isolated Limb Infusion.- Induction treatment in sarcomas.- Isolated Limb Perfusion for Locally Advanced Soft Tissue Sarcoma.- Induction Chemotherapy in Treatment of Sarcomas.- Isolation Perfusion Systems: Lungs.- Metastatic Cancers in Lung: Isolated Lung Perfusion - Clinical Studies.- Isolated Thoracic Perfusion with Chemofiltration (ITP-F) for Advanced and Pre-treated Non-Small-Cell Lung

Professor Dr. med. Aigner is one of the world's pioneers in the field of regional chemotherapy. He has been involved with regional chemotherapy for over 30 years and today he is considered as one of the world's most experienced experts in this treatment method. Numerous lectures and guest operations in the USA, Japan, China, Israel, Egypt, Australia and a number of other countries, as well as over 200 professional publications, lectures and guest operations both in Germany and abroad attest to his medical commitment to RCT - regional chemotherapy.Prof. Aigner completed his medical studies and his basic surgical training in cardiovascular surgery at the University of Erlangen. He obtained his habilitation doctorate in surgical oncology at the University of Giessen, with a research focus in techniques of regional chemotherapy. In 1981, Prof Aigner developed a technique for performing the first isolated liver perfusion in humans using a heart-lung machine, and over subsequent years a variety of additional surgical procedures and specialized catheters for isolated therapy of organs and parts of the body, including the treatment of pancreatic carcinoma.From 1986 until 1991, Prof. Aigner was Chief Physician for Surgery at the Kreiskrankenhaus Trostberg am Chiemsee, and until 2001, he was the Chief Physician in the Department of Oncological Surgery at the Asklepios Paulinen Clinic in Wiesbaden. From 2002 until 2005 he led the Department of oncological surgery at the Medias Klinik GmbH in Ransbach-Baumbach. Since 2006 Prof. Aigner has been the Medical Director of the Medias Klinikum GmbH & Co KG, a private clinic for oncological surgery in Burghausen (Salzach).Professor Emeritus Fred Stephens is a global authority in innovative approaches to the treatment of previously incurable cancers. From his base at Sydney University, Professor Stephens was an early pioneer in Regional Chemotherapy, with experience spanning over four decades. His remarkable results gained