Interferon:

- Reflections

1.1 Jean Linndemann: How to chase a red herring and come up with a Smallmouth Bass

1.2 J. Vilcek: Interferon research before BC (before cloning)

1.3 S. Pestka: Purification and cloning of Interferon Alpha

- Interferons and their signaling pathways

2.1 P. Pitha and M. Kunzi: Type I Interferon: the ever unfolding story

2.2 G. Uze, G. Schreiber, J. Piehler and S. Pellegrini: The receptor of the type I interferon family

2.3 H. Young and J. Bream: IFN: Recent Advances I Understanding Regulation of Expression, Biological Functions and Clinical Application

2.4 A. van Boxel-Dezaire and G. Stark: Cell Type -Specific Signaling in response to Interferon gamma

2.5 J. Darnell: Interferon Research; Impact on understanding transcriptional control

- Recognition of pathogens, molecular mechanism of interferon beta induction

3.1 M. Severa and K. Fitzgerald: TLR-mediated activation of type I IFN during antiviral immine responses:fighting the battle to win the war

3.2 K. Onomoto, M. Yopeneyma and T. Fujita: Regulation of Antiviral Immune Response by RIG-I family of RNA helicases

3.3 M.Schlee, W.Barchets, V.Hornung and G.Hartmann: Beyond double stranded RNA-type I IFN induction by 3pRNA and other viral nucleic acids

- Interferon induced genes

4.1 G. Sen and S. Sarkar: The Interferon-Stimulated Genes: Targets of direct signaling by interferon, double -stranded RNA and viruses

4.2 A.Sadler and B. Williams: Structure and Function of the Protein Kinase R

- Virus defense

5.1 Y-M Loo and M. Gale: Viral Regulation and Evasion of the host response

5.2. O.Haller and F.Weber: Pathogenic Viruses: Smart Manipulators of the Interferon System

- Role of interferon in viral infection and autoimmunity

6.1 E. Zuniga, B. Hahm and M. Oldstone: Type I IFN during viralinfection: multiple triggers for a multifunctiona mediator

6.2 S. Crow: Type I FN in Systemic Lupus Erythematosus

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Subject Index

From the reviews: