Midkine: From Embryogenesis to Pathogenesis and Therapy
(Sprache: Englisch)
Carl Edward Sagan¿s (1934-1996) one of the famous quotation was ¿Who are we? We find that we live on an insignificant planet of a humdrum star lost in a galaxy tucked away in some forgotten corner of a universe in which there are far more galaxies than...
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Klappentext zu „Midkine: From Embryogenesis to Pathogenesis and Therapy “
Carl Edward Sagan¿s (1934-1996) one of the famous quotation was ¿Who are we? We find that we live on an insignificant planet of a humdrum star lost in a galaxy tucked away in some forgotten corner of a universe in which there are far more galaxies than people.¿ From past to date, well-known molecules, enzymes, proteins, lipids and carbohydrates are studied in the pathogenesis of several diseases both as a diagnostic/prognostic biomarker and therapeutic agent. The underlying mechanism of unexplained diseases and failure of therapies are frequently studied with well-known biomarkers, but remain unclear in many cases. As Dr. Sagan said other keys are still waiting to be known in some forgotten corner of a body universe, we find strength to propose that one of them can be the growth factor with cytokine activity named ¿Midkine¿ This book summarizes the extensive up-to-date literature overeview with the lastest work of experts about midkine in a detailed format that conveys its role as both a pathologic factor and therapeutic agent.
Inhaltsverzeichnis zu „Midkine: From Embryogenesis to Pathogenesis and Therapy “
PART I: GENERAL ASPECTS OF MIDKINECHAPTER 1 General information on midkineCHAPTER 2 The role of midkine in neural development and patterningCHAPTER 3 Midkine- A player in innate immunityCHAPTER 4 Midkine/p63 axis in regulation of epithelial-mesenchymal transitionCHAPTER 5 Immunochemical methods for the detection of midkine in samples of human originCHAPTER 6 Circulating midkine in malignant, inflammatory, and infectious diseases: a systematic review PART II: MIDKINE AND INFLAMMATIONCHAPTER 7 Midkine in inflammation and inflammatory diseasesCHAPTER 8 Rheumatoid arthritis and midkine PART III: MIDKINE AND THE CARDIOVASCULAR SYSTEMCHAPTER 9 Midkine and heart failureCHAPTER 10 Vascular restenosis and midkineCHAPTER 11 The potential of MK through the renin-angiotensin system PART IV: MIDKINE AND THE NERVOUS SYSTEM CHAPTER 12 Midkine and Multiple sclerosisCHAPTER 13 MK gene transfer in brain infarctionCHAPTER 14 Midkine in psychiatric and neurodegenerative diseases PART V: MIDKINE AND THE UROGENITAL SYSTEM, REPRODUCTION AND AGINGCHAPTER 15 Role of midkine in nephrogenesis and kidney Disease CHAPTER 16 Midkine, a factor promoting cytoplasmic maturation of oocytesCHAPTER
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17 Endometriosis may be promoted by midkine: possible involvement of ovarian folliclesCHAPTER 18 Stem cells and midkineCHAPTER 19 Midkine in skeletal physiologyPART VI MIDKINE AND CANCERCHAPTER 20 Midkine and chemotherapy resistance in cancersCHAPTER 21 A gene medicine with the midkine transcriptional regulation as new cancer therapeuticsCHAPTER 22 Midkine as a tumor shared antigenCHAPTER 23 Midkine in prostate cancerCHAPTER 24 Midkine is a potential therapeutic target of hepatocellular carcinomaCHAPTER 25 Midkine in glioblastoma with the modulator role switching autophagy to cell death or cell survivalCHAPTER 26 Colon cancer and midkineCHAPTER 27 Osteosarcoma and midkineIndex.
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Bibliographische Angaben
- 2012, 2012, 338 Seiten, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Mine Ergüven, Ayhan Bilir, Takashi Muramatsu
- Verlag: Springer Netherlands
- ISBN-10: 9400742339
- ISBN-13: 9789400742338
- Erscheinungsdatum: 23.05.2012
Sprache:
Englisch
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