NF-kB in Health and Disease
(Sprache: Englisch)
Nearly 25 years of research have uncovered many diverse functions for the dimeric transcription factor NF-kappaB. NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation.
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Nearly 25 years of research have uncovered many diverse functions for the dimeric transcription factor NF-kappaB. NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation.
Klappentext zu „NF-kB in Health and Disease “
Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation
Inhaltsverzeichnis zu „NF-kB in Health and Disease “
Preface.- Understanding the Logic of IkappaB:NF-kappaB Regulation in Structural Terms.- IKK regulation and human genetics.- Specialized chromatin patterns in the control of inflammatory gene expression.- Macrophages and NF-kappaB in Cancer.- NF- B/Rel proteins and the humoral immune responses of Drosophila melanogaster.- IKK and NF-kappaB mediated functions in carcinogenesis.- Control of NF-kappaB activity by proteolysis.- NF-kappaB as a target for oncogenic viruses.- NF-kappaB and Innate Immunity.- Inhibition of NF-kappaB signaling as a strategy in disease therapy.- NF- B and mucosal homeostasis.- NF-kappaB In liver cancer - the plot thickens.- Subject index.
Bibliographische Angaben
- 2013, VIII, 268 Seiten, Maße: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Herausgegeben: Michael Karin
- Verlag: Springer, Berlin
- ISBN-10: 364226803X
- ISBN-13: 9783642268038
Sprache:
Englisch
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