Nonmalignant Hematology
Expert Clinical Review: Questions and Answers
(Sprache: Englisch)
This book, in Q&A format, addresses a wide range of clinically relevant topics and issues in Nonmalignant Hematology, or "Benign Hematology," with a view to offering a robust, engaging tool that will assist every hematologist and oncologist (pediatric...
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This book, in Q&A format, addresses a wide range of clinically relevant topics and issues in Nonmalignant Hematology, or "Benign Hematology," with a view to offering a robust, engaging tool that will assist every hematologist and oncologist (pediatric and adult equally) in making decisions during day-to-day practice. The entire spectrum of the specialty is covered in more than 60 exceptional chapters written by acknowledged authorities in the field. The content is organized into well-designed broad sections on red cell disorders, platelet and coagulation disorders, coagulopathy in systemic diseases, thromboembolic disease and its management (including surgical), immune system and related disorders, hemostasis and thrombosis during pregnancy and in the newborn and elderly, and Transfusion Medicine. A key aspect of the book is the opportunity it affords expert physicians to express well-reasoned opinions regarding complex issues in Nonmalignant Hematology. Readers will find that it provides a practical and immediately applicable compendium of answers to often complex and vexing questions. It will appeal to residents, fellows, house officers and more experienced practitioners around the globe.Inhaltsverzeichnis zu „Nonmalignant Hematology “
Part 1. Red Blood Cells.- Evaluation of anemia in children and adults.- Iron cycle and pathophysiology of iron homeostasis.- Porphyrias: Diagnosis and management.- Disorders of hemoglobin synthesis: Pathophysiology and diagnostic evaluation.- Management of thalassemias.- Allogeneic hematopoietic cell transplant in ß-thalassemia major.- Sickle cell disease: Prevention of complications.- Sickle cell disease: Management of complications.- Allogeneic hematopoietic cell transplant in sickle cell disease.- Anemia of inflammation.- Iron overload: Diagnosis, complications and management.- Megaloblastic and nutritional anemias.- Sideroblastic anemias: Diagnosis and management.- Primary autoimmune warm antibody hemolytic anemias.- Intrinsic hemolytic anemias: Pathophysiology, diagnosis and management.- Part 2. Platelets and Coagulation System.- Platelet disorders: Diagnostic tests and their interpretations.- Inherited platelet disorders: Diagnosis and management.- Acquired platelet disorders: Diagnosis and management.- Immune mediated thrombocytopenia.- Coagulation cascade and fibrinolysis pathway: Assessment in the laboratory.- Abnormalities in fibrinolysis pathway and clinical implications.- Congenital disorders of fibrinogen: Clinical presentations, diagnosis and management.- Hemophilias A and B: Diagnosis and management.- Coagulation factor inhibitors: Diagnosis and management.- Rare coagulation factor deficiencies: Diagnosis and management.- von Willebrand disease: Differential diagnosis and diagnostic approach to specific subtypes.- von Willebrand disease: Prevention of complications and management of the disease.- Antifibrolytics: Indications and precautions.- Gene therapy for bleeding disorders.- Part 3. Coagulopathy in Systemic Diseases.- Disseminated intravascular coagulopathy.- Coagulopathy in critically ill subjects.- Trauma-associated coagulopathy.- Coagulation related issues in malignant hematology: Diagnosis and management.- Unmet clinical
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needs of antithrombotic treatment in BCR/ABL negative myeloproliferative neoplasms.- Bleeding and thrombosis in a cancer patient.- Management of surgical patient with thrombotic and bleeding diathesis.- Part 3. Thrombosis and Therapeutics.- Prevention and treatment of arterial thromboembolism.- mes New Roman","serif"">Prevention of venous thromboembolism.- Diagnostic, prognostic and therapeutic challenges in venous thromboembolisim.- Complications of venous thromboembolic disease.- Hereditary thrombophilias: Pathophysiology, timing of testing and familiar testing.- Anti-phospholipid antibodies and syndrome: Complexities in diagnosis and management.- Unidentifiable thrombophilias.- Anticoagulation drugs: Indications, therapeutic monitoring and antidotes.- Heparin induced thrombocytopenia: Diagnosis and management.- Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.- Surgical treatment of thromboembolic disease.- Part 4. Immune System and Related Disorders.- Nonmalignant leukocyte disorders.- Primary immunodeficiency disorders: Diagnosis and management.- Disorders of phagocytic function: Diagnosis and treatment.- Inherited bone marrow failure syndromes.- Hemophagocytic lymphohistiocytosis: Diagnosis and management challenges.- Lysosomal storage disorders: Hematology perspective.- Cryoglobulins and cryoglobulinemia.- Part 5. Hemostasis and Thrombosis in Pregnancy, Newborn and Elderly.- Reproductive issues in women with bleeding and thrombotic disorders.- Pregnancy in subjects with hemoglobinopathies: Precautions and management.- Neonatal thrombosis and coagulopathies.- Bleeding and thrombosis in elderly.- Part 6. Transfusion Medicine.- Transfusion support: Indications, efficacy and complications.- Human blood antigens and antibodies: Diagnostic and therapeutic implications.- Therapeutic apheresis in hematologic disorders: When and Why?
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Autoren-Porträt
SyedAbutalib isAssistant Director of Hematology and Blood and Marrow Hematopoietic CellTransplant Program. Dr. Abutalib earned his medical degree from Dow MedicalCollege in Karachi, Pakistan and subsequently completed a residency in InternalMedicine at Cook County Hospital and a Fellowship in Hematology/Oncology at theUniversity of Illinois at Chicago. During his Fellowship he participated inLeukemia Research at Northwestern Hospital & University of Chicago. Boardcertified in Internal Medicine, Medical Oncology and Hematology, Dr. Abutalibspecializes in benign hematology, malignant hematology and hematopoietic bloodand marrow cell transplant. Dr. Abutalib has been published in severalpeer-reviewed journals, including the American Journal of Hematology, CurrentPharmaceutical Biotechnology, and the American Journal ofClinical Pathology and has written chapters for medicaltextbooks, including Acute Leukemias (2008), Evidence-BasedHematology(2008), Expert Hematology & Oncology Essentials (2014)and Cancer Consult-Expertise for Clinical Practice (2014),Essential Oncology (2015). Dr. Abutalib is the editor of several booksincluding, Cancer Consult-Expertise for Clinical Practice publishedon behalf of Blackwell Wiley Health Sciences. He is on the editorial boardfor Clinical Oncology News and THE ASCO POST magazineand contributes regularly in the column " HowI Manage.." and "Expert Hematology Review",respectively. Besides his Patients he hold Medical Education dear to hisheart. Jean M. Connors is an Assistant Professor ofMedicine at Harvard Medical School. Dr Connors received her medical degree fromJohns Hopkins University School of Medicine in Baltimore, Maryland. Shecompleted residency in Internal Medicine at Beth Israel Hospital, Boston,Massachusetts, and fellowships in both Hematology/Oncology and TransfusionMedicine at Brigham and Women's Hospital, Boston. Dr Connors cares for patientswith inherited and acquired thrombotic and
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coagulation disorders. AsMedical Director of the Brigham and Women's Hospital and Dana Farber CancerInstitute Anticoagulation Management Service, Dr Connors overseesanticoagulation practices in outpatient clinical settings. She is also theMedical Director of the Hemostatic Antithrombotic Stewardship program, amulti-disciplinary care delivery program, to ensure judicious and optimal useof anticoagulants and clotting factors across all BWH inpatient services. Shehas participated in a variety of types of clinical trials focusingon anticoagulation including investigator initiated, served on scientificadvisory boards for a number of companies, teaches extensively at many levelsincluding peers in CME courses as well as fellows and residents, and haswritten numerous reviews and chapters in the area of thrombosis-hemostasis.
MargaretRagni is aProfessor of Medicine and Clinical Translational Science at the Universityof Pittsburgh Medical Center, Pittsburgh, Pennsylvania. She received her MDfrom the University of Pittsburgh School of Medicine and a Master of PublicHealth from the University of Pittsburgh School of Public Health. She completedher residency and fellowship in hematology/oncology at the University ofPittsburgh Medical Center in Pittsburgh, where she joined the faculty in 1983.Dr. Ragni's research interests are in congenital and acquired disorders ofhemostasis and thrombosis, and, in, particular in novel therapeutics forpatients with hemophilia with and without inhibitors. She serves on the Medicaland Scientific Advisory Committee of the National Hemophilia Foundation (NHF),the FDA Blood Products Advisory Committee, the Scientific Committee onHemostasis of the American Society of Hematology, and on the Medical AdvisoryBoard for
MargaretRagni is aProfessor of Medicine and Clinical Translational Science at the Universityof Pittsburgh Medical Center, Pittsburgh, Pennsylvania. She received her MDfrom the University of Pittsburgh School of Medicine and a Master of PublicHealth from the University of Pittsburgh School of Public Health. She completedher residency and fellowship in hematology/oncology at the University ofPittsburgh Medical Center in Pittsburgh, where she joined the faculty in 1983.Dr. Ragni's research interests are in congenital and acquired disorders ofhemostasis and thrombosis, and, in, particular in novel therapeutics forpatients with hemophilia with and without inhibitors. She serves on the Medicaland Scientific Advisory Committee of the National Hemophilia Foundation (NHF),the FDA Blood Products Advisory Committee, the Scientific Committee onHemostasis of the American Society of Hematology, and on the Medical AdvisoryBoard for
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Bibliographische Angaben
- 2018, Softcover reprint of the original 1st ed. 2016, XVI, 718 Seiten, 59 farbige Abbildungen, Maße: 18,1 x 25,4 cm, Kartoniert (TB), Englisch
- Herausgegeben: Syed A. Abutalib, Jean M. Connors, Margaret V. Ragni
- Verlag: Springer, Berlin
- ISBN-10: 3319807870
- ISBN-13: 9783319807874
Sprache:
Englisch
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