Oxidation: The Cornerstone of Carcinogenesis
This book is unique due to its collective approach to the key aspects of the interdependency between three entities: oxidative stress, tobacco smoke and carcinogenesis, operating in a cause-effect sequence, in a concise and to the point manner. This book...
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This book is unique due to its collective approach to the key aspects of the interdependency between three entities: oxidative stress, tobacco smoke and carcinogenesis, operating in a cause-effect sequence, in a concise and to the point manner. This book will prove to be a helpful companion to the internist, the oncologist and the research scientist in molecular biology as well as a work of reference for the general practitioner and physician interested in cancer research.
2: Oxidative stress
3: Oxidative damage of genome DNA: repair mechanisms
4: Mitochondria: structure, function and relationship with carcinogenesis
5: Oxidative activation of transcription factor pathways by cigarette smoke oxidants
6: Cell protection mechanisms from oxidation
7: Role of DNA adducts in carcinogenesis
8: Transmolecular reactions of genetic toxicity: alkylation and methylation of DNA
9: Toxicity and carcinogenicity of hydrocarbons
10: Toxicity and carcinogenicity of the aromatic hydrocarbons
11: Toxicity and carcinogenicity of aldehydes
12: Toxicity and carcinogenicity of the nitriles
13: Toxicity and carcinogenicity of the eterocyclic organic compounds
14: Toxicity and carcinogenicity of metals
15: Oxidative profile of cigarette smoke and lung cancer
16: Smoking and lung cancer
John C. Stavridis is a medical doctor who studied Medicine at the Military Medical School of Thessaloniki, Greece. He specialized in Internal Medicine at the Evangelismos Medical Centre, Athens, and received his MD and Professorship from the University of Athens Medical School. Following a postdoctoral position as a senior research fellow and registrar at postgraduate Medical School, London University, Hammersmith Hospital, Department of Clinical Hematology, he joined the Hematology Unit at St. Sabbas Anticancer Hospital, Athens, as director. He taught Physiology from 1991-1999 as a head of the Department of Physiology and full professor at the University of Athens Medical School. Since 1999, Prof. Stavridis has been President of the Institute of Biomedical Research and Biotechnology, Athens.
- Autor: John C. Stavridis
- 2008, 2008, 258 Seiten, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Verlag: Springer Netherlands
- ISBN-10: 1402067038
- ISBN-13: 9781402067037
- Erscheinungsdatum: 21.01.2008
"The book "Oxidation: The Cornerstone of Carcinogenesis" by Professor J. C. Stavridis represents a monumental work of correlating oxidation as the common pathway of causing cell damage to the bronchoepithelial cells and carcinogenesis utilized by the various tobacco smoke constituents. ...This book by Prof. Stavridis is a significant intellectual feat of the first order, bringing original insights and a comprehensive review of an area that heretofore had been unaccountably neglected." (Dr. Constantine Karakousis, Professor of Surgical Oncology)
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