Peptide Synthesis and Applications

Solid-Phase Peptide Synthesis: An Introduction.- Linkers, Resins and General Procedures for Solid-phase Peptide Synthesis.- Peptide Release, Side-chain Deprotection, Work-up, and Isolation.- Synthesis of Peptides using Tert-butyloxycarbonyl (Boc) as the -amino Protection Group.- Sequential Formation of Regioselective Disulfide Bonds in Synthetic Peptides with Multiple Disulfide Bonds.- Synthesis of Cyclic Disulfide-Rich Peptides.- Preparation of C-terminally Modified Chemokines by Expressed Protein Ligation.- Synthesis of C-terminal Peptide Thioesters using Fmoc Based Solid-phase Peptide Chemistry.- Backbone Amide Linker Strategy -Protocols for the Synthesis of C terminal Peptide Aldehydes.- Synthesis of N-methylated Peptides: On-resin Methylation and Microwave-Assisted Couplings.- Synthesis of Antimicrobial Peptoids.- Synthesis of Lipidated Peptides.- Solid-Phase Synthesis of Phosphopeptides.- Synthesis of O-Glycopeptides and Construction of Glycopeptide Microarrays.- Instruments for Automated Peptide Synthesis.- Microwave-Assisted Solid-Phase Peptide Synthesis using the Biotage Syro Wave(TM).- Microwave-Assisted Solid-Phase Peptide Synthesis Based on the Fmoc Protecting Group Strategy (CEM).