Pharmaceutical Powder and Particles

Introduction.- Importance of Finely Divided Solids in Pharmaceutical Dosage Forms.- Solid State Chemistry.- Crystallization.- Physical Properties.- Particle Size and Size Distribution.- Particle Size Characterization.- Fundamental of Particle Interactions.- Powder and Particle Dependent Traditional Manufacturing Processes (unit operations).-  Powder and Particle Dependent Biopharmaceutical Processes.-  Recent and Evolving Manufacturing Processes.-  Principles of Quality by Design.-  General Discussion.

Anthony Hickey, Ph.D., is a Distinguished RTI Fellow (appointed June 2012), and a senior research pharmacologist at RTI International. Dr. Hickey has more than 30 years of academic and research experience in pulmonary biology, aerosol physics, powder dynamics, pharmacokinetics and drug disposition, formulation design, and device development. Since joining RTI in 2011, he has conducted research related to pulmonary drug and vaccine delivery for tuberculosis treatment and prevention and directed a program in nanotechnology informatics. Additionally, Dr. Hickey is an adjunct professor of biomedical engineering at the University of North Carolina at Chapel Hill School of Medicine, emeritus professor of molecular pharmaceutics at the University of North Carolina at Chapel Hill, Eshelman School of Pharmacy, and founder of Cirrus Pharmaceuticals, Inc., Oriel Therapeutics, Inc. and Astartein LLC. He has received many awards and honors and is an active member of several professional societies and committees, including the  American Association for Aerosol Research, American Chemical Society, International Association of Colloid and Interface Scientists, International Society for Aerosols in Medicine, and the Society of Toxicology. He is a fellow of  the American Association of Pharmaceutical Scientists, the American Association for the Advancement of Science, the Royal Society of Biology and Royal Society of Medicine. Dr. Hickey holds 25 patents and has authored numerous books, book chapters, and more than 200 journal articles.
Stefano Giovagnoli graduated in chemistry in 1997 at the University of Perugia. After being R&D researcher at the GlaxoSmithKlein, Ware, England, he completed his Ph.D. studies on micro- and nanoparticulate systems for the delivery of antioxidants and proteins at the University of Perugia, spending part of his doctoral work at the University of Kentucky,Lexington, Kentucky, in the laboratories