Protein Kinase CK2 Cellular Function in Normal and Disease States

1. CK2 Suppression of Apoptosis Khalil Ahmed? (co-editor)
2. Structural Determinants of CK2 Regulation by Autoinhibitory Oligomerization Roberto Battistutta, Department of Chemistry, University of Padua, Italy
3. Targeting Protein Kinase: CK2 Suppresses Pro-Survival Signaling Pathways and Growth of Gliobastoma Tika Benveniste, Department of Neurobiology, University of Alabama-Birmingham
4. The Roles of CK2 in Drosophila Neurogenesis Ashok Bidwai, Department of Biology, University of West Virginia
5. Targeting the CK2 Subunit Interface: Challenge and Usefulness Claude Cochet, Institute of Sciences Research and Technologies, Grenoble, France
6. CK2 in Wnt/?-catenin signaling and embryo development.Isabel Maria Dominguez, Boston University School of Medicine
7. Defective expression of CK2? promotes EMT and stemness properties both required for breast cancer progression Odile Filhol, Institute of Sciences Research and Technologies, Grenoble, France
8. Chemical Biology Approaches to Identify CK2 Substrates and Perform Unbiased Evaluation of CK2 Inhibitors Michelle Gabriel, Western University, Canada
9. Development of Screening Systems and Identification of Novel Potent Inhibitors of Human Protein Kinase CK2 Joachim Jose, Institute of Pharmaceutical and Medicinal Chemistry, The University of Muenster, Germany
10. Protein Kinase CK2: At the Crossroad of Regulatory Cellular Pathways David Litchfield, Professor and Chair of the Dept of Biochemistry, Western University, Canada
11. Functional Regulation of DYRK Family Protein Kinases by Cellular Binding Partners Yoshihiko Miyata, Dept of Cell and Developmental Biology, Kyoto University, Japan
12. Regulation of CK2 in pancreatic ? cells Mathias Montenarh, Faculty of Medicine, Saarlandes University, Germany
13. Recent impressions from the configurational and conformational space captured by protein kinase CK2 Karsten Niefind, Department of Chemistry, University of Cologne, Germany
14. Role of CK2 in

Dr. Khalil Ahmed is a Professor at the University of Minnesota, and a Senior Research Career Scientist at Minneapolis VA Health Care System, Minneapolis, Minnesota, U.S.A. He has a long history of studies on the functional biology of protein kinase CK2 in normal and neoplastic cells. He originally described the signal mediated dynamic shuttling of CK2 in the cell, and discovered the role of CK2 as a suppressor of apoptosis. His current research is focused on the mechanism of CK2 regulation of cell death. He is also studying the development of molecular therapeutic strategies using a nanomedicine approach for treatment of prostate and other cancers. Dr. Olaf-Georg Issinger is a Professor at the University of Southern Denmark, Odense, Denmark. He has been involved in the initial cloning and characterization of protein kinase CK2, a prerequisite for the elucidation of its structure in the absence and presence of specific interaction molecules. His current research focuses on the exploration of cellular signaling pathways in cell lines with respect to the role of various protein kinases using newly characterized kinase inhibitors identified by screening small chemical compound libraries.Dr. Ryszard Szyszka is a Professor at the John Paul II Catholic University of Lublin, Poland. He is head of the Department of Molecular Biology and Dean of the Faculty of Biotechnology and Environmental Sciences. His research is focused on the identification and characterization of new substrates of protein kinase CK2 from Saccharomyces cerevisiae. Further areas of interest include the structure and regulation of yeast CK2, and discovery of novel CK2 inhibitors.