Synthesis and Therapeutic Effects of Alkylglycerols
(Sprache: Englisch)
The active ingredients in the natural shark liver oil (SLO) mixture were found to be a group of ether-linked glycerol known as alkylglycerols (AKGs). During the last century, initial clinical use of the SLO mixture was for treating leukemias, and later...
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The active ingredients in the natural shark liver oil (SLO) mixture were found to be a group of ether-linked glycerol known as alkylglycerols (AKGs). During the last century, initial clinical use of the SLO mixture was for treating leukemias, and later preventing radiation sickness from cancer x-ray therapy. Currently, resistance to the existing drugs and increasing numbers of diseases result in identifying new drugs candidates with new forms of activities. Consequently, natural and non-natural synthesized AKGs could be one new source of drug delivery systems. This book focuses on the medicinal chemistry of new potential drugs, with alklyglycerols as undeniable source. In chapter 1, we review the beneficial effects of alkylglycerols. In chapter 2, we discuss a consise and highly efficient synthetic process for a natural bioactive 2-methoxyalkyl glycerol ether analogue. In chapter 3, we feature the synthesis of bioactive non-natural alkylglycerols. Overall, the chapters in this book point natural and non-natural synthesized AKGs as one new source of drugs delivery system, but remind us of the cope in developing new efficient routes to 1-O-alkylglycerols.
Autoren-Porträt von René Pemha, Dr. René MOMHA
Dr. René MOMHA received his PhD in synthetic organic chemistry from the University of Rennes 1 in 2011. After the completion of his degree, he worked as a Postdoctoral researcher in medicinal chemistry at the University of Health Network and University of Toronto. Dr. Pemha has published several research papers in scientific journals.
Bibliographische Angaben
- Autoren: René Pemha , Dr. René MOMHA
- 2020, 56 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 3330029862
- ISBN-13: 9783330029866
Sprache:
Englisch
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