Synthesis of Heterocycles via Cycloadditions I
(Sprache: Englisch)
Heterocyclic chemistry is the biggest branch of chemistry covering two-thirds of the chemical literature. This series covers hot topics of frontier research summarized by reputed scientists in the field.
Voraussichtlich lieferbar in 3 Tag(en)
versandkostenfrei
Buch (Kartoniert)
219.99 €
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenlose Rücksendung
- Ratenzahlung möglich
Produktdetails
Produktinformationen zu „Synthesis of Heterocycles via Cycloadditions I “
Heterocyclic chemistry is the biggest branch of chemistry covering two-thirds of the chemical literature. This series covers hot topics of frontier research summarized by reputed scientists in the field.
Klappentext zu „Synthesis of Heterocycles via Cycloadditions I “
Heterocyclicmoleculesplayasigni?cantroleinlifeprocessesandhaveplayed a major rolein industrial developments of the last century, for instance in the ?eld of dyes, pharmaceuticals, pesticides, polymers etc. They comprise not onlysomeofthemostinterestingandbiologicallyimportantnaturalproducts like alkaloids, carbohydrates, nucleic acids, and antibiotics but include many practical drugs and a large segment of known synthetic organic compounds. Hencescientistshavedevotedagreatamountofeffortto?ndoptimalsynthetic approachesto a variety ofheterocyclic compounds. Amongthemostsuccessfulandselectivesyntheticprocessesarecycload- tionreactions,since theyinvolvesimultaneous orsequential formationoftwo ormorebondsoftenwithahighdegreeofstereoselectivityandregioselectivity. Forinstance, 1,3 dipolar cycloadditionsareelectronicallyequivalent to Diels Alder reactions and are among the most common 5-membered ring-forming systems. In addition they usually proceed with a high degree of stereo- and regio-control.It is therefore, not surprising that synthesis of many important classesofheterocycles,includingthoseofusefulbiologicallyactivemolecules, haveutilized cycloadditionsteps intheir formation.Furthermore,manyhe- rocyclesserve as intermediates in the synthesis of polyfunctional molecules. In this volume we present ?ve selected contributions by well-known - thors, each an authority in his ?eld. The ?rst chapter deals with construction ofisoxazolines(dihydroisoxazoles)via1,3-dipolarcycloadditionsofnitronates or of nitrile oxides generated from nitroalkanes. This includes inter- as well as intramolecular processes. Many of these heterocycles possess important synthetic and biological properties and are shown to lead to stereo- and - gioselectiveintroductionofmultifunctionalmoleculessuchasaminoalcohols, ?-amino acids, aldols, nitriles, and others.
Inhaltsverzeichnis zu „Synthesis of Heterocycles via Cycloadditions I “
Isoxazolines from Nitro Compounds: Synthesis and Applications.- Cycloaddition Reactions of Azides Including Bioconjugation.- Enantioselective Cycloadditions of Azomethine Ylides.- Heterocycles by Cycloadditions of Carbonyl Ylides Generated from Diazo Ketones.- Heterocycles from Unsaturated Phosphorus Ylides.
Bibliographische Angaben
- 2010, XII, 229 Seiten, Maße: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Herausgegeben: Alfred Hassner
- Verlag: Springer, Berlin
- ISBN-10: 3642097081
- ISBN-13: 9783642097089
Sprache:
Englisch
Kommentar zu "Synthesis of Heterocycles via Cycloadditions I"
Schreiben Sie einen Kommentar zu "Synthesis of Heterocycles via Cycloadditions I".
Kommentar verfassen