The Development of New Methods toward Guaiane Natural Products
The Use of Irontricarbonyl Cyclobutadiene in Total Synthesis
(Sprache: Englisch)
Guaiane natural products are complex architectures that contain multiple stereogenic centers, ring junctures, and functionalities that render their synthesis difficult without an efficient and effective methodology. Herein, a new method for generating these...
Leider schon ausverkauft
versandkostenfrei
Buch
81.30 €
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenlose Rücksendung
- Ratenzahlung möglich
Produktdetails
Produktinformationen zu „The Development of New Methods toward Guaiane Natural Products “
Klappentext zu „The Development of New Methods toward Guaiane Natural Products “
Guaiane natural products are complex architectures that contain multiple stereogenic centers, ring junctures, and functionalities that render their synthesis difficult without an efficient and effective methodology. Herein, a new method for generating these natural products will be discussed. In particular, highly strained intermediates, generated through an intramolecular cyclobutadiene cycloaddition, will be studied and utilized. The following are a summary of the chapters:Chapter 1: Tricyclo[3.2.0.02,4]heptanes are unique scaffolds that possess many interesting chemistries. A review of both their synthesis and chemistry is covered.Chapter 2: Syn-tethered tetracyclo[5.3.0.01,5.02,4]decanes are strained systems obtained through a cyclobutadiene cycloaddition-intramolecular cyclopropanation sequence. Studies related to these systems will be covered.Chapters 3 and 4: An intramolecular cyclobutadiene cycloaddition-cyclopropanation-thermal fragmentation methodology is utilized for the asymmetric total synthesis of two guaiane natural products. In addition, the methodology is further expanded upon to access multiple guaianes from a single intermediate.
Autoren-Porträt von Michael Williams
Williams, MichaelMichael J. Williams earned his undergraduate degree in chemistry at the University of Illinois in 2001, and, under the direction of Professor Marc L. Snapper, received his doctorate in organic chemistry from Boston College in 2007. After graduation, he began working at the Schering-Plough Research Institute as a medicinal chemist.
Bibliographische Angaben
- Autor: Michael Williams
- 2008, 420 Seiten, Maße: 15 x 22 cm, Kartoniert (TB), Englisch
- Verlag: VDM Verlag Dr. Müller e.K.
- ISBN-10: 3836496410
- ISBN-13: 9783836496414
- Erscheinungsdatum: 14.11.2013
Sprache:
Englisch
Kommentar zu "The Development of New Methods toward Guaiane Natural Products"
Schreiben Sie einen Kommentar zu "The Development of New Methods toward Guaiane Natural Products".
Kommentar verfassen