Biomedical Applications (PDF)
The mechanical properties of cells can be used to distinguish pathological from normal cells and tissues in many diseases. This book will outline the physics behind cell and tissue mechanics, describe the methods which can be used to determine their...
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The mechanical properties of cells can be used to distinguish pathological from normal cells and tissues in many diseases. This book will outline the physics behind cell and tissue mechanics, describe the methods which can be used to determine their mechanical properties, and present various diseases in which a mechanical fingerprint could be established. The book is designed to not require a background in either Physics or Life Sciences.
M. Lekka, Polish Acad. of Sci., Poland;
D. Navajas, U. Barcelona, Spain;
A. Podestà, U. Milan, Italy;
M. Radmacher, U. Bremen, Germany.
Since 1999, AP is active in the field of characterization of physical and chemical properties of systems and interfaces at the nanoscale by Atomic Force Microscopy (AFM) techniques. AP leads the AFM group of the Interdisciplinary Centre for Nanostructured Materials and Interfaces (CIMaINa) of Università degli Studi di Milano. The research activity of the AFM laboratory developed over the years under the guidance of AP since its foundation in 1999, along two parallel but strongly interconnected tracks: the development of experimental techniques and protocols based on atomic force microscopy, and the application of such protocols to the study of nanostructured systems and interfaces. The synergistic combination of research and development activities related to atomic force microscopy has always characterized the scientific approach of AP within the Physics Department and CIMAINA @UNIMI; this expertise has been enhanced at European and international level in funded research projects and in commissioned research activities.
The main activities of AP are the following:
1. Development of Atomic Force Microscopy techniques for the study of systems and interfaces at the nanoscale: metrology of nanometer-sized objects (proteins and nanoparticles); nanomechanical characterization of soft matter systems; force spectroscopy; production and calibration of AFM probes.
2. Study of
3. Study of nanostructured interfaces and inorganic systems: evolution of surface morphology, wettability, electric properties of thin nanostructured films; interfacial properties of thin ionic liquids films supported on solid surfaces.
AP is the coordinator of the MSCA-ITN training and research network Phys2BioMed (www.phys2biomed.eu), dedicated to the development of diagnostic approaches based on the quantitative study of the biomechanical properties of cells and tissues. AP is member of the Academic Board of the PhD school in Physics, Astrophysics and Applied Physics of the University of Milan. AP supervises BSc, MSc and PhD students' as well as post-doc research projects.
- 2023, 1. Auflage, 370 Seiten, Englisch
- Herausgegeben: Alessandro Podestà, Malgorzata Lekka, Daniel Navajas, Manfred Radmacher
- Verlag: Walter de Gruyter GmbH & Co.KG
- ISBN-10: 3110989387
- ISBN-13: 9783110989380
- Erscheinungsdatum: 20.02.2023
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