Channels, Carriers, and Pumps (PDF)
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An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered.
- Provides an introduction to the properties of transport proteins: channels, carriers, and pumps
- Presents up-to-date information on the structure of transport proteins and on their function and regulation
- Includes introductions to transport kinetics and to the cloning of genes that code transport proteins
- Furnishes a link between the experimental basis of the subject and theoretical model building
- Autoren: Wilfred D. Stein , Thomas Litman
- 2014, 2. Auflage, 422 Seiten, Englisch
- Verlag: Elsevier Science & Techn.
- ISBN-10: 0124165834
- ISBN-13: 9780124165830
- Erscheinungsdatum: 09.12.2014
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
- Dateiformat: PDF
- Größe: 44 MB
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Praise for the previous edition: "It has become the "Bible" for my lab" --Tony Carruthers, Dean, Graduate School of Biomedical Sciences, UMass Medical School
"The strength of this book is the way in which rigorous yet lucid expositions of the theoretical basis of various types of transport are integrated with illuminating discussions of experimental results. [This book] will continue to be rewarding reading when many symposium reports have become outdated, and it is warmly welcomed and recommended." --D.K. Apps, FEBS LETTERS, August 1991
"With so much diversity in biology it is exhilarating to read Stein’s attempt at synthesis. More of this is needed . . . Stein’s book should earn a place of its own, for it does something that few others attempt: it puts channels, carriers, and pumps under one roof . . . the book’s greatest value: its potential for catalytic action on sometimes disparate fields." --Louis J. DeFelice, California Institute of Technology, CELL, August 1991
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