Discovery of Small-Molecule Modulators of Protein-RNA Interactions for Treating Cancer and COVID-19 / Springer Theses (PDF)
Modulating...
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Modulating protein-RNA interactions with small molecules is expected to provide novel biological insights of the interrelation of diseases with the protein-RNA interactome. The modulations may also be exploited therapeutically. For these reasons, the development of a simple, reliable, and sensitive protein-RNA-binding assay is necessary for high-throughput screening to discover new effective chemical entities capable of acting on diverse protein-RNA interactions. This book discusses the discovery of small-molecule modulators targeting protein-RNA interactions that are potentially valuable to treat cancer and COVID-19 by constructing novel high-throughput screening methods. The results of this dissertation provide valuable insights into the regulation of protein-RNA interactions in chemical biology and drug development.
- Autor: Wan Gi Byun
- 2022, 1st ed. 2023, 128 Seiten, Englisch
- Verlag: Springer Nature Singapore
- ISBN-10: 981197814X
- ISBN-13: 9789811978142
- Erscheinungsdatum: 13.12.2022
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