Heterocyclic Chemistry (PDF)
(Sprache: Englisch)
This book has so closely matched the requirements of its
readership over the years that it has become the first choice for
chemists worldwide.
Heterocyclic chemistry comprises at least half of all organic
chemistry research worldwide. In particular,...
readership over the years that it has become the first choice for
chemists worldwide.
Heterocyclic chemistry comprises at least half of all organic
chemistry research worldwide. In particular,...
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This book has so closely matched the requirements of its
readership over the years that it has become the first choice for
chemists worldwide.
Heterocyclic chemistry comprises at least half of all organic
chemistry research worldwide. In particular, the vast majority of
organic work done in the pharmaceutical and agrochemical industries
is heterocyclic chemistry.
The fifth edition of Heterocyclic Chemistry maintains the
principal objective of earlier editions - to teach the
fundamentals of heterocyclic reactivity and synthesis in a way that
is understandable to second- and third-year undergraduate chemistry
students. The inclusion of more advanced and current material also
makes the book a valuable reference text for postgraduate taught
courses, postgraduate researchers, and chemists at all levels
working with heterocyclic compounds in industry.
Fully updated and expanded to reflect important 21st
century advances, the fifth edition of this classic text includes
the following innovations:
* Extensive use of colour to highlight changes in structure and
bonding during reactions
* Entirely new chapters on organometallic heterocyclic chemistry,
heterocyclic natural products, especially in biochemical processes,
and heterocycles in medicine
* New sections focusing on heterocyclic fluorine compounds,
isotopically labeled heterocycles, and solid-phase chemistry,
microwave heating and flow reactors in the heterocyclic
context
Essential teaching material in the early chapters is followed by
short chapters throughout the text which capture the essence of
heterocyclic reactivity in concise resumés suitable as
introductions or summaries, for example for examination
preparation. Detailed, systematic discussions cover the reactivity
and synthesis of all the important heterocyclic systems. Original
references and references to reviews are given throughout the text,
vital for postgraduate teaching and for research scientists.
Problems, divided into straightforward revision exercises, and more
challenging questions (with solutions available online), help the
reader to understand and apply the principles of heterocyclic
reactivity and synthesis.
readership over the years that it has become the first choice for
chemists worldwide.
Heterocyclic chemistry comprises at least half of all organic
chemistry research worldwide. In particular, the vast majority of
organic work done in the pharmaceutical and agrochemical industries
is heterocyclic chemistry.
The fifth edition of Heterocyclic Chemistry maintains the
principal objective of earlier editions - to teach the
fundamentals of heterocyclic reactivity and synthesis in a way that
is understandable to second- and third-year undergraduate chemistry
students. The inclusion of more advanced and current material also
makes the book a valuable reference text for postgraduate taught
courses, postgraduate researchers, and chemists at all levels
working with heterocyclic compounds in industry.
Fully updated and expanded to reflect important 21st
century advances, the fifth edition of this classic text includes
the following innovations:
* Extensive use of colour to highlight changes in structure and
bonding during reactions
* Entirely new chapters on organometallic heterocyclic chemistry,
heterocyclic natural products, especially in biochemical processes,
and heterocycles in medicine
* New sections focusing on heterocyclic fluorine compounds,
isotopically labeled heterocycles, and solid-phase chemistry,
microwave heating and flow reactors in the heterocyclic
context
Essential teaching material in the early chapters is followed by
short chapters throughout the text which capture the essence of
heterocyclic reactivity in concise resumés suitable as
introductions or summaries, for example for examination
preparation. Detailed, systematic discussions cover the reactivity
and synthesis of all the important heterocyclic systems. Original
references and references to reviews are given throughout the text,
vital for postgraduate teaching and for research scientists.
Problems, divided into straightforward revision exercises, and more
challenging questions (with solutions available online), help the
reader to understand and apply the principles of heterocyclic
reactivity and synthesis.
Inhaltsverzeichnis zu „Heterocyclic Chemistry (PDF)“
Preface Definitions of abbreviations 1. Heterocyclic nomenclature 2. Structures and spectroscopic properties of aromatic heterocycles 3. Substitutions of aromatic heterocycles 4. Organometallic heterocyclic chemistry 5. Methods in heterocyclic chemistry 6. Ring synthesis of aromatic heterocycles 7. Typical reactivity of pyridines, quinolines and isoquinolines 8. Pyridines: reactions and synthesis 9. Quinolines and isoquinolines: reactions and synthesis 10. Typical reactivity of pyrylium and benzopyrylium ions, pyrones and benzopyrones 11. Pyryliums, 2- and 4-pyrones: reactions and synthesis 12. Benzopyryliums, benzopyrones: reactions and synthesis 13. Typical reactivity of the diazines: pyridazine, pyrimidine and pyrazine 14. The diazines: pyridazine, pyrimidine, and pyrazine: reactions and synthesis 15. Typical reactivity of pyrroles, thiophenes, and furans 16. Pyrroles: reactions and synthesis 17. Thiophenes: reactions and synthesis 18. Furans: reactions and synthesis 19. Typical reactivity of indoles, benzo[b]thiophenes, benzo[b]furans, isoindoles, benzo[c]thiophenes and isobenzofurans 20. Indoles: reactions and synthesis 21. Benzo[b]thiophenes and benzo[b]furans: reactions and synthesis 22. Isoindoles, benzo[c]thiophenes and isobenzofurans: reactions and synthesis 23. Typical reactivity of 1,3- and 1,2-azoles and benzo-1,3- and -1,2-azoles 24. 1,3-Azoles: imidazoles, thiazoles, and oxazoles: reactions and synthesis 25. 1,2-Azoles: pyrazoles, isothiazoles, isoxazoles: reactions and synthesis 26. Benzanellated azoles: reactions and synthesis 27. Purines: reactions and synthesis 28. Heterocycles containing a ring-junction nitrogen (bridgehead compounds) 29. Heterocycles containing more than two heteroatoms 30. Saturated and partially unsaturated heterocyclic compounds: reactions and synthesis 31. Special topics 32. Heterocycles in biochemistry; heterocyclic natural products 33. Heterocycles in medicine
Autoren-Porträt von John A. Joule, Keith Mills
John Joule is Emeritus Professor in the School of Chemistry,The University of Manchester, UK
Keith Mills spent 25 years in the Medicinal Chemistry and
Development Chemistry departments at GlaxoSmithKline, Stevenage,
UK, and is now an independent consultant.
Bibliographische Angaben
- Autoren: John A. Joule , Keith Mills
- 2010, 5. Auflage, 640 Seiten, Englisch
- Verlag: John Wiley & Sons
- ISBN-10: 0470685972
- ISBN-13: 9780470685976
- Erscheinungsdatum: 16.02.2010
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