Life-Threatening Effects of Antipsychotic Drugs (ePub)
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Life-Threatening Effects of Antipsychotic Drugs describes in detail more than 20 life-threatening effects associated with antipsychotics, presents the best available data on their incidence and case fatality, and gives comprehensive advice on diagnosis, management and preventive strategies. In addition, the book discusses the benefit of antipsychotic medication in a range of therapeutic indications, and demonstrates the gain in life-expectancy associated with clozapine use in severe mental illness despite its serious, potentially life-threatening adverse effects.
- Covers cardiovascular, neurological, muscular, hematological, gastrointestinal, autonomic and metabolic effects
- Gives advice on risk factors, confounding diagnoses and measures to minimise seriousness
- Discusses clozapine rechallenge after each of its serious adverse reactions
- Makes suggestions for optimum management of somatic disease in those with severe mental illness, to improve life-expectancy
- Includes data on post-mortem considerations
Professor Bob Flanagan is Consultant Clinical Scientist and Director, Toxicology Unit, King’s College Hospital NHS Foundation Trust and Clinical Lead for Toxicology, Sheffield Teaching Hospital NHS Foundation Trust. He has published over 200 scientific papers and four books. Particular interests have been treatment of mental illness especially as regards use of antipsychotics, notably clozapine, treatment of cancer, especially in respect of the use of tyrosine kinase inhibitors such as imatinib, and the diagnosis of substance abuse, especially misuse of volatiles such as butane. He led on toxicology training for the Association for Clinical Biochemistry for many years, and regularly advises medical professionals, police, coroners, and prosecution and defence lawyers on toxicological issues. He has also acted as a consultant to the United Nations Office for Drugs and Crime, most recently as regards advising on methodology for the detection of drug-facilitated crime, and to the World Health Organization, notably in Serbia/Kosovo in 2007, and also in the Middle East and in India. He is immediate past-President of the British Academy of Forensic Sciences.
- 2016, 394 Seiten, Englisch
- Herausgegeben: Peter Manu, Robert J. Flanagan, Kathlyn J. Ronaldson
- Verlag: Elsevier Science & Techn.
- ISBN-10: 0128033908
- ISBN-13: 9780128033906
- Erscheinungsdatum: 16.08.2016
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
- Dateiformat: ePub
- Größe: 10 MB
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- Vorlesefunktion
All subjects are treated in a consistent manner, starting with an epidemiological overview, followed by some background regarding pathobiology, continuing over clinical signs to management, ending up with suggestions for prevention of the conditions. The book has a richness of tables and figures facilitating the reading and understanding of the book’s important information and many messages of, e.g. Hazard ratios, odds ratios, clinical algorithms, all making it easily accessible.
… The book is highly relevant to the clinically working psychiatrist, his/her assistants, medical students and other with interest in the interphase between psychiatric illnesses, somatic diseases, their treatment and the always present balance between effect and side effects of treatments." --Mikkel Hojlund, Povl Munk-Jørgensen, Nordic Journal of Psychiatry
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