Model Organisms to Study Biological Activities and Toxicity of Nanoparticles (PDF)
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Thanks to their high surface-to-volume ratio, nanoparticles are characterized by excellent biocompatibility and bioavailability, a high therapeutic index, and relatively low toxicity, which has led to their widespread application in the early diagnosis of diseases, comprehensive monitoring of disease progression, and improved therapeutics.
The book also explores nanoparticle-based insecticides and their mechanisms of action, and provides a comparative analysis of the various model organisms that are used to understand the biological properties of nanoparticles. Further, it describes various in-vivo models that yield important insights into nanomaterial-mediated toxicity, promoting the optimal utilization of nanoparticles. In closing, the book discusses future perspectives and regulatory issues concerning the use of nanomaterials in translational research.
Dr. Madhu Dyavaiah is an Assistant Professor, in the Department of Biochemistry and Molecular Biology; Pondicherry University, Pondicherry. He has earlier served as Research Scientist in the College of Nanoscale Science and Engineering, Albany, USA (2010-2012), Postdoctoral associate at Gen'NY'sis Center for Excellence in Cancer Genomic Rensselaer, USA (2006-2010), Postdoctoral fellow at Wadsworth Center, USA (2003-2006) and IISc. Bangalore, India (2002-2003). His research interest includes, DNA damage response, tRNA modification and translation regulation and aging biology. He has worked in the area of nanotechnology in USA, and research experience different model systems including plant, S. cerevsiae, cell lines and mice. Currently, he is working S.
Dr. Kaviyarasu Kasinathan obtained his Master of Science (M.Sc.) & Master of Philosophy (M.Phil.) degree in Physics from Loyola College (Autonomous), Chennai, affiliated to the University of Madras, India. Dr. Kaviyarasu Kasinathan was awarded a Senior Research Fellow (SRF) by Tamil Nadu State Council of Science and Technology (TNSCST) and completed a Doctor of Philosophy degree in Physics at Manonmaniam Sundaranar University (MSU), India. He has carried out research on multifunctional metal oxide nanoparticles for energy and biomedical applications. During the course of his research work, he has published total no. of peer reviewed publications - 125 in International and national journals and delivered 35 oral/invited talks on nanomaterials; thin films; photocatalysis; biomaterials; solar energy conversion; preparation techniques and characterization studies in conferences, universities and academic institutions. Currently, at present working as a Research Scientist at iThemba LABS, Cape Town his research is directed primarily toward developing and applying modern material design for the understanding and prediction of materials science research with ion beams has been basically developed by nuclear/material physicists. It started with the development of acceleratorbased techniques for materials characterization, leading into surface studies and depth profiling. Now the swift heavy ions are being utilized for engineering the properties of materials and are exploited in almost all the emerging new areas in materials science. Our goal is to understand how to design and control the nanoscale organization of macromolecular nanomaterials and their nanocomposites in order to achieve improved structure, properties, and functionality. His research interests include bulk and nanoscaled materials for solid state physics, and multifunctional metal oxide nanomaterial.
- 2020, 1st ed. 2020, 466 Seiten, Englisch
- Herausgegeben: Busi Siddhardha, Madhu Dyavaiah, Kaviyarasu Kasinathan
- Verlag: Springer-Verlag GmbH
- ISBN-10: 9811517029
- ISBN-13: 9789811517020
- Erscheinungsdatum: 28.03.2020
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