Molecular Diagnostics (ePub)
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Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter.
Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the battery of the most widely used molecular pathology techniques. New chapters have been added, including the various new technologies involved in next-generation sequencing (mutation detection, gene expression, etc.), mass spectrometry, and protein-specific methodologies.
All revised chapters have been completely updated, to include not only technology innovations, but also novel diagnostic applications. As with previous editions, each of the chapters in this section includes a brief description of the technique followed by examples from the area of expertise from the selected contributor.
The second part of the book attempts to integrate previously analyzed technologies into the different aspects of molecular diagnostics, such as identification of genetically modified organisms, stem cells, pharmacogenomics, modern forensic science, molecular microbiology, and genetic diagnosis. Part three focuses on various everyday issues in a diagnostic laboratory, from genetic counseling and related ethical and psychological issues, to safety and quality management.
- Presents a comprehensive account of all new technologies and applications used in clinical diagnostic laboratories
- Explores a wide range of molecular-based tests that are available to assess DNA variation and changes in gene expression
- Offers clear translational presentations by the top molecular pathologists, clinical chemists, and molecular geneticists in the field
Prof. Dr. George P. Patrinos; University of Patras School of Health Sciences, Department of Pharmacy, Patras, Greece; United Arab Emirates University, College of Medicine and Health Sciences, Department of Pathology, Al-Ain, UAE; Erasmus University Medical Center, School of Medicine and Health Sciences, Department of Pathology - Bioinformatics Unit, Rotterdam, the Netherlands
Prof. Dr. Wilhelm Ansorge is a Senior Research Scientist and coordinator of the Biochemical Instrumentation Programme at the European Molecular Biology Laboratory in Heidelberg, Germany. His research interests include the development of the first complete Human Genome microarray, with numerous applications in gene expression studies and high-throughput Molecular Diagnostics.
Phillip B. Danielson is Professor of Molecular Biology at the University of Denver and is the Science Advisor for the National Law
- 2016, 3. Auflage, 520 Seiten, Englisch
- Herausgegeben: George P. Patrinos, Wilhelm Ansorge, Phillip B. Danielson
- Verlag: Elsevier Science & Techn.
- ISBN-10: 0128029889
- ISBN-13: 9780128029886
- Erscheinungsdatum: 27.10.2016
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
- Dateiformat: ePub
- Größe: 114 MB
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