Neuropathology Simplified (PDF)

David Hilton is an experienced diagnostic neuropathologist working in one of the UK's largest hospitals in Plymouth and is a fellow of both the UK Royal College of Pathologists and Physicians. His practice covers all areas of adult neuropathology, including neurosurgical pathology, autopsy work, and neuromuscular disease (including the undertaking of muscle and nerve biopsies on patients). In addition he is actively involved in research, including aspects of neurodegenerative disease and tumour biology, and has published over 85 peer reviewed research articles and written several book chapters, covering many aspects of neuropathology.

Selected publications:

Schwannomas and their pathogenesis. D.A.Hilton, C.O.Hanemann. Brain Pathology 2014; 24(3): 205-20.

Accumulation of alpha synuclein in the bowel of patients in the pre-clinical phase of Parkinson's disease. D.A.Hilton, M.Stephens, L.Kirk, P.Edwards, R.Potter, J.Zajicek, E.Broughton, H.Hagan, C.Carroll. Acta Neuropathologica 2014; 127(2): 235-41.

Dipeptide repeat pathology in a frontotemporal dementia kindred with C9ORF72 mutation and intellectual disability. M.Proudfoot, N.J.Gutowski, D.Edbauer, D.A.Hilton, M.Stephens, J.Rankin, I.R. A.Mackenzie. Acta Neuropathologica 2014; 127(3):451-8.

Axl/Gas6/NF¿B signalling in schwannoma pathological proliferation, adhesion and survival. S.Ammoun, L.Provenzano, L., M.C.Schmid, L.Zhou, M.Barczyk, K.Evans, D.A.Hilton, S.Hafisi, C.O.Hanemann. Oncogene 2014; 33(3): 336-46.

Quantification of mitochondrial changes in muscle from individuals without muscle disease; comparison with mitochondrial disorders. K.Sleigh, S.Ball, D.A.Hilton. Muscle and Nerve 2011; 46(6): 795-800.

Aditya Shivane has been working as a Consultant Neuropathologist in Derriford Hospital, Plymouth since 2009. He graduated from India in 1998. After completing post-graduation (MD, taught) in Pathology from Mumbai University (2001) he worked briefly as