Redox Proteomics / Wiley-Interscience Series on Mass Spectrometry (PDF)
From Protein Modifications to Cellular Dysfunction and Diseases
(Sprache: Englisch)
Methodology and applications of redox proteomics
The relatively new and rapidly changing field of redox proteomics
has the potential to revolutionize how we diagnose disease, assess
risks, determine prognoses, and target therapeutic strategies...
The relatively new and rapidly changing field of redox proteomics
has the potential to revolutionize how we diagnose disease, assess
risks, determine prognoses, and target therapeutic strategies...
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Methodology and applications of redox proteomics
The relatively new and rapidly changing field of redox proteomics
has the potential to revolutionize how we diagnose disease, assess
risks, determine prognoses, and target therapeutic strategies for
people with inflammatory and aging-associated diseases. This
collection brings together, in one comprehensive volume, a broad
array of information and insights into normal and altered
physiology, molecular mechanisms of disease states, and new
applications of the rapidly evolving techniques of
proteomics.
Written by some of the finest investigators in this area, Redox
Proteomics: From Protein Modifications to Cellular Dysfunction and
Diseases examines the key topics of redox proteomics and redox
control of cellular function, including:
* The role of oxidized proteins in various disorders
* Pioneering studies on the development of redox proteomics
* Analytical methodologies for identification and structural
characterization of proteins affected by oxidative/nitrosative
modifications
* The response and regulation of protein oxidation in different
cell types
* The pathological implications of protein oxidation for
conditions, including asthma, cardiovascular disease, diabetes,
preeclampsia, and Alzheimer's disease
Distinguished by its in-depth discussions, balanced methodological
approach, and emphasis on medical applications and diagnosis
development, Redox Proteomics is a rich resource for all
professionals with an interest in proteomics, cellular physiology
and its alterations in disease states, and related fields.
The relatively new and rapidly changing field of redox proteomics
has the potential to revolutionize how we diagnose disease, assess
risks, determine prognoses, and target therapeutic strategies for
people with inflammatory and aging-associated diseases. This
collection brings together, in one comprehensive volume, a broad
array of information and insights into normal and altered
physiology, molecular mechanisms of disease states, and new
applications of the rapidly evolving techniques of
proteomics.
Written by some of the finest investigators in this area, Redox
Proteomics: From Protein Modifications to Cellular Dysfunction and
Diseases examines the key topics of redox proteomics and redox
control of cellular function, including:
* The role of oxidized proteins in various disorders
* Pioneering studies on the development of redox proteomics
* Analytical methodologies for identification and structural
characterization of proteins affected by oxidative/nitrosative
modifications
* The response and regulation of protein oxidation in different
cell types
* The pathological implications of protein oxidation for
conditions, including asthma, cardiovascular disease, diabetes,
preeclampsia, and Alzheimer's disease
Distinguished by its in-depth discussions, balanced methodological
approach, and emphasis on medical applications and diagnosis
development, Redox Proteomics is a rich resource for all
professionals with an interest in proteomics, cellular physiology
and its alterations in disease states, and related fields.
Autoren-Porträt
ISABELLA DALLE-DONNE, PHD, is Assistant Professor in theDepartment of Biology at the University of Milan, Italy. She has a
PhD in cellular and molecular biology from the University of Milan.
ANDREA SCALONI, PHD, is First Investigator at the
Proteomics & Mass Spectrometry Laboratory, ISPAAM, National
Research Council in Naples, Italy. He received his PhD in chemical
sciences from the University of Rome "La Sapienza" in Italy.
D. ALLAN BUTTERFIELD, PHD, is Alumni Professor of
Chemistry and Director of the University of Kentucky Center of
Membrane Sciences in Lexington, Kentucky, USA. He received his PhD
in physical chemistry from Duke University.
Bibliographische Angaben
- 2006, 1. Auflage, 960 Seiten, Englisch
- Herausgegeben: Isabella Dalle-Donne, Andrea Scaloni, D. Allan Butterfield
- Verlag: John Wiley & Sons
- ISBN-10: 0471973114
- ISBN-13: 9780471973119
- Erscheinungsdatum: 25.07.2006
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