A Network-Based Approach to Cell Metabolism / Springer Theses (PDF)

Name: A Network-Based Approach to Cell Metabolism / Springer Theses
Brand: Springer-Verlag GmbH
SKU: 103500889
Price: 98.99 EUR
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From Structure to Flux Balances (Sprache: Englisch)

Autor: Oriol Güell

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This thesis uses a systems-level approach to study the cellular metabolism, unveiling new mechanisms and responses that were impossible to reach with traditional reductionists procedures.

The results reported here have a potential application in...

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This thesis uses a systems-level approach to study the cellular metabolism, unveiling new mechanisms and responses that were impossible to reach with traditional reductionists procedures.

The results reported here have a potential application in areas like metabolic engineering and disease treatment. They could also be used in determining the accuracy of the gene essentiality of new genome-scale reconstructions.

Different methods and techniques, within the contexts of Systems Biology and the field known as Complex Networks Analysis have been applied in this work to show different features of the robustness of metabolic networks. The specific issues addressed here range from pure topological aspec

ts of the networks themselves to the balance of biochemical fluxes.

Autoren-Porträt von Oriol Güell

Oriol Güell holds a Ph.D. in Physical Chemistry from the University of Barcelona, Spain, and has broad experience in the theoretical modelling and the experimental applications of magnetic colloidal dispersions and in the computer modelling of metabolic networks. Currently, his main research focuses on obtaining and applying bio-based polymers and plasticisers and studying their associated physicochemical properties.