The Kinesin Superfamily Handbook (PDF)
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This book brings together current information on the families that make up the kinesin superfamily of molecular motors in one comprehensive text; an ideal reference for researchers looking to make comparisons between different families, for specific information on an individual family, or simply for an overview of the kinesin superfamily.
Information is clearly structured and grouped according to individual families and organised in a standardised way, allowing the reader to easily search and retrieve information on this large superfamily of molecular motors and understand how its individual members carry out a diverse variety of cellular functions.
Features
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- The first book dedicated to the entire kinesin superfamily
- Enables a fuller understanding of this family of proteins, which is becoming an increasing focus of research due to its involvement in diseases such as cancer, neuropathies and ciliopathies
- Written in a manner accessible to a range of researchers in the life and medical sciences, including biophysicists, biochemists and medical researchers.
Chapters 4 and 11 of this book are freely available as downloadable Open Access PDFs at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.
Claire T. Friel earned a BSc in Biochemistry from the University of Glasgow, UK, and carried out her PhD work on protein folding kinetics in the laboratory of Sheena Radford at the University of Leeds, UK. In 2006, she joined the group of Jonathon Howard at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany. There, she solved the ATP turnover cycle of the microtubule depolymerising Kinesin-13, MCAK, and developed an interest in the kinesin superfamily of molecular motors. Since 2011, Claire has held the position of Assistant Professor at the University of Nottingham, UK. The research goals of the Friel lab are to understand the relationship between the kinesin motor domain sequence and the many functional properties of the kinesin superfamily and to understand the molecular mechanisms of proteins that regulate microtubule dynamics.
- 2020, 186 Seiten, Englisch
- Herausgegeben: Claire T. Friel
- Verlag: Taylor & Francis
- ISBN-10: 0429958250
- ISBN-13: 9780429958250
- Erscheinungsdatum: 13.05.2020
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- Größe: 55 MB
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