The Molecular Biology of Cancer (PDF)

Stella Pelengaris PhD is a Senior Research Fellow in
Molecular Medicine in the Department of Biological Sciences at the
University of Warwick and Warwick Medical School. While working as
a PDRA at the Imperial Cancer Research Fund, she established a
series of unique model systems for studying the role of c-Myc and
apoptosis in cancer initiation and reversal. Since 1999 she and
Mike Khan have jointly run the cancer biology research group at the
University of Warwick where, in collaboration with Gerard Evan,
they have confirmed the inherent tumor-suppressor activity of c-Myc
(apoptosis) as a major barrier to oncogenic deregulation of c-Myc.
The group is currently researching the role of c-Myc in both
oncogenesis and in the apoptosis of beta cells in diabetes.

Mike Khan PhD FRCP is a Consultant Endocrinologist and
Physician at the University Hospitals of Coventry and Warwickshire
and Head of Molecular Medicine at the University of Warwick and
Warwick Medical School. He was elected as a Fellow of the Royal
College of Physicians in 2002 and as a Member of the Association of
Physicians in 2004. His main research interests have been in the
regulation of tissue growth and plasticity during development and
in adult tissue homeostasis. Currently, he is collaborating with
mathematicians and others in a systems biology approach to define
key functional gene and protein networks involved in regulating
cell fate.

Dr Khan and Dr Pelengaris jointly run various postgraduate
training courses at masters level and beyond in cancer biology and
in lipid metabolism/diabetes. They also are coauthors of the
textbook Lipids and Diabetes (2002).

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