Epilepsy
Animal and Human Correlations
(Sprache: Englisch)
The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized....
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Produktinformationen zu „Epilepsy “
The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized. Specific cogent animal studies/results which deserve exploration in human seizure disorders will be detailed. The current rate of translation is estimated to be from 7?9 years, and the "success" rate of translation was very recently listed as less than one half. The success rate is defined as results in human studies which were predicted in advance by animal studies. Both the time between animal and human attempts plus the success rate need improvement.
Klappentext zu „Epilepsy “
The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized. Specific cogent animal studies/results which deserve exploration in human seizure disorders will be detailed. The current rate of translation is estimated to be from 7-9 years, and the "success" rate of translation was very recently listed as less than one half. The success rate is defined as results in human studies which were predicted in advance by animal studies. Both the time between animal and human attempts plus the success rate need improvement.
The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. Typical as well as atypical seizures are described, and whenever possible studies in primates receive careful attention.
Inhaltsverzeichnis zu „Epilepsy “
- Prologue: World Health Concerns, Incidence, Costs, etcSection 1 Animal Partial
Chapter 1: Simple Partial
Chapter 2: Complex Partial
Section 2 Animal Generalized
Chapter 3: Tonic Clonic
Chapter 4: Tonic
Chapter 5: Atonic
Chapter 6: Myoclonic
Chapter 7: Absence
Section 3 Animal
Chapter 8: Unclassified-Mixed
Chapter 9: Nocturnal
Section 4 Human Partial
Chapter 10: Simple Partial
Chapter 11: Simple complex
Section 5 Human Generalized
Chapter 12: Tonic Clonic
Chapter 13: Tonic
Chapter 14: Atonic
Chapter 15: Myoconic
Chapter 16: Absence
Section 6 Human
Chapter 17: Unclassified-Mixed
Chapter 18: Nocturnal
Section 7 Miscellaneous
Chapter 19: Pediatric Considerations
Chapter 20 : Surgery
Chapter 21: Status Epilepticus
Chapter 22: Epilogue Animal Generalized
Chapter 3: Tonic Clonic
Chapter 4: Tonic
Chapter 5: Atonic
Chapter 6: Myoclonic
Chapter 7: Absence
Section 3 Animal
Chapter 8: Unclassified-Mixed
Chapter 9: Nocturnal
Section 4 Human Partial
Chapter 10: Simple Partial
Chapter 11: Simple complex
Section 5 Human Generalized
Chapter 12: Tonic Clonic
Chapter 13: Tonic
Chapter 14: Atonic
Chapter 15: Myoconic
Chapter 16: Absence
Section 6 Human
Chapter 17: Unclassified-Mixed
Chapter 18: Nocturnal
Autoren-Porträt von David W. McCandless
The work of Dr. David W. McCandless spanned over 35 years of laboratory research into basic mechanisms of various metabolic encephalopathies. He was the Founding Editor of the journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently, he served as the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA.
Bibliographische Angaben
- Autor: David W. McCandless
- 2011, XV, 532 Seiten, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Verlag: Springer, Berlin
- ISBN-10: 1461401089
- ISBN-13: 9781461401087
- Erscheinungsdatum: 01.11.2011
Sprache:
Englisch
Rezension zu „Epilepsy “
From the reviews:"For the clinical neurologists and epileptologists dedicated to the care of children and adults affected with epilepsy, a concise book like Epilepsy ... is a good attempt to become a source for those seeking rapid immersion in the essentials of translational epilepsy research that have tried to explain those critical aspects of epileptogenesis that involve acquired and developmental seizures. ... it is a good foundation for those looking for a quick initial reference, which may not be available in rapidly accessible vast internet sources." (Luis E. Bello-Espinosa, The Canadian Journal of Neurological Sciences, Vol. 40 (1), January, 2013)
Pressezitat
"This is a comprehensive text and atlas on animal and human studies of Epilepsy. ... I highly recommend this book to the following audiences: students, fellows, researchers, neurologists, neurosurgeons, and undergraduates." (Joseph J. Grenier, Amazon.com, September, 2015)"For the clinical neurologists and epileptologists dedicated to the care of children and adults affected with epilepsy, a concise book like Epilepsy ... is a good attempt to become a source for those seeking rapid immersion in the essentials of translational epilepsy research that have tried to explain those critical aspects of epileptogenesis that involve acquired and developmental seizures. ... it is a good foundation for those looking for a quick initial reference, which may not be available in rapidly accessible vast internet sources." (Luis E. Bello-Espinosa, The Canadian Journal of Neurological Sciences, Vol. 40 (1), January, 2013)
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