Mass Spectrometry Imaging

Introductory Reviews and Tutorials.- Imaging Mass Spectrometry: Viewing the Future.- A Mass Spectrometry Primer for Mass Spectrometry Imaging.- Imaging of Metals, Metalloids, and Non-metals by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) in Biological Tissues.- Protocols for MS Imaging of Distribution of Small Molecules Including Metabolites and Pharmaceuticals.- Lipid Detection, Identification, and Imaging Single Cells with SIMS.- The Application and Potential of Ion Mobility Mass Spectrometry in Imaging MS with a Focus on Lipids.- Quantitative Imaging of Chemical Composition in Single Cells by Secondary Ion Mass Spectrometry: Cisplatin Affects Calcium Stores in Renal Epithelial Cells.- Imaging MALDI Mass Spectrometry of Sphingolipids Using an Oscillating Capillary Nebulizer Matrix Application System.- Mapping Pharmaceuticals in Rat Brain Sections Using MALDI Imaging Mass Spectrometry.- Laser Ablation Electrospray Ionization for Atmospheric Pressure Molecular Imaging Mass Spectrometry.- Matrix-Assisted Laser Desorption/Ionization and Nanoparticle-Based Imaging Mass Spectrometry for Small Metabolites: A Practical Protocol.- Cellular Imaging Using Matrix-Enhanced and Metal-Assisted SIMS.- Tandem Mass Spectrometric Methods for Phospholipid Analysis from Brain Tissue.- Chemical Imaging with Desorption Electrospray Ionization Mass Spectrometry.- Mass Spectrometry Imaging of Small Molecules Using Matrix-Enhanced Surface-Assisted Laser Desorption/Ionization Mass Spectrometry (ME-SALDI-MS).- Preparation of Single Cells for Imaging Mass Spectrometry.- Applying Imaging ToF-SIMS and PCA in Differentiation of Tissue Types.- Protocols for MS Imaging of Distribution of Peptides and Proteins.- Direct Molecular Analysis of Whole-Body Animal Tissue Sections by MALDI Imaging Mass Spectrometry.- MALDI Direct Analysis and Imaging of Frozen Versus FFPE Tissues: What Strategy for Which Sample?.- On Tissue Protein Identification Improvement by N-Terminal

From the reviews:"The book aims to provide comprehensive background information on mass spectrometry imaging (MSI) technology ... . a monograph that has the merit of summarizing many protocols of great value for all scientists, engineers, and clinicians who are interested in applying MSI in their work. The book is clearly written and comprehensive, and has a good balance between theoretical descriptions and broad practical descriptions. Both established MSI researchers and those new to the field would benefit from this valuable source of methodological information." (José Manuel Costa-Fernández, Analytical and Bioanalytical Chemistry, Vol. 401, 2011)