Mouse Models for Drug Discovery

Genetically Defined Strains in DrugDevelopment and Toxicity Testing.- Simple, Efficient CRISPR-Cas9Mediated Gene Editing in Mice: Strategies and Methods.- Mouse Sperm Cryopreservation andRecovery of Genetically Modified Mice.- Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftmentof Hematopoietic Stem Cells.- Generation of Human Liver ChimericMice for the Study of Human Hepatotropic Pathogens.- Human FcRn Transgenic Mice forPharmacokinetic Evaluation of Therapeutic Antibodies.- A Humanized Mouse Model to StudyHuman Albumin and Albumin Conjugates Pharmacokinetics.- Germ-Free Mice Model for StudyingHost-Microbial Interactions.- Bridging Mice to Men: Using HLATransgenic Mice to Enhance the Future Prediction and Prevention of AutoimmuneType 1 Diabetes in Humans.- Mouse Models of Type 2 DiabetesMellitus in Drug Discovery.- Cholesterol Absorption andMetabolism.- Skin Diseases in Laboratory Mice:Approaches to Drug Target Identification and Efficacy Screening.- Chronic Myeloid Leukemia (CML) MouseModel in Translational Research.- Murine Model for Colitis-AssociatedCancer of the Colon.- Mouse Models for StudyingDepression-Like States and Antidepressant Drugs.- Experimental Models of Anxiety forDrug Discovery and Brain Research.- Repetitive Behavioral Assessmentsfor Compound Screening in Mouse Models of Autism Spectrum Disorders.- Better Utilization of Mouse Modelsof Neurodegenerative Diseases in Preclinical Studies: From the Bench to theClinic.- Neuromuscular Disease Models andAnalysis.- Brightfield Imaging and Optical Coherence Tomography of the MousePosterior Eye.- MouseModels as Tools to Identify Genetic Pathways for Retinal Degeneration, asExemplified by Leber's Congenital Amaurosis.