Multiple Sclerosis and Related Disorders

Section 1 Pathogenesis 1. Immune regulation of multiple sclerosis   2. Neuropathology of MS  3. The good and the bad of neuroinflammation in multiple sclerosis  4. Demyelination in multiple sclerosis  5. Axonal loss in multiple sclerosis: Causes and mechanisms   6. Insights from magnetic resonance imaging  7. Infections and multiple sclerosis  8. The experimental autoimmune encephalomyelitis (EAE) model of MS: utility for understanding disease pathophysiology and treatment

Section 2 Epidemiology and genetics 9. Multiple sclerosis genetics  10. Genetics of primary progressive multiple sclerosis  11. The epidemiology of multiple sclerosis: insights to disease pathogenesis

Section 3 Diagnosis and disease course 12. Multiple Sclerosis: Diagnosis, differential diagnosis and clinical presentation  13. MRI mimics of multiple sclerosis  14. Diagnosis of multiple sclerosis  15. Clinical course of multiple sclerosis  16. Early prognosis of multiple sclerosis  17. Clinical outcome measures in multiple sclerosis  18. MRI outcomes in the diagnosis and disease course of multiple sclerosis   19. Multiple sclerosis in children

Section 4 Treatment 20. Clinical trials in multiple sclerosis  21. Glucocorticoid treatment of multiple sclerosis  22. Disease modifying agents in multiple sclerosis  23. Immunosuppressive treatments in multiple sclerosis  24. Symptomatic treatment and management of multiple sclerosis  25. Future treatment approaches to multiple sclerosis 

Section 5 Other demyelinating diseases 26. Neuromyelitis optica (Devic's syndrome)  27. Acute disseminated encephalomyelitis and other inflammatory demyelinating variants  28. Acute inflammatory myelopathies 

Section 6 Capita selecta 29. Clinical neurophysiology of multiple sclerosis  30. Cerebrospinal fluid analysis

An Exploration into China's Economic Development and Electricity Demand by the Year 2050, is an exploratory study of national and regional economic development, energy demand and electricity demand in China by the year of 2050. China's economy grows rapidly and it is now the second largest economy in the world. In 2010, GDP reached 40 trillion Yuan and electricity consumption was second only to the United States, reaching 4.19 trillion kWh. Many people follow future (long-term) trends of Chinese economic development and demand for electricity closely and are especially interested in how development will look in 2030 and 2050.

Based on the ILE4, this book examines the main features of China's economic development and electricity consumption since the economic reform of the 1980's. It includes an analysis of the intrinsic connection between electricity demand and economic growth and the changing trends of the adjustment of economic structure, regional layout optimization and development of the energy intensive industry, as well as how these factors impact China's demand for electricity. In addition, the book considers the next 20 years of China's economic development and growing demand for electricity based on the detailed simulations conducted by ILE4 in regional economic development and electricity consumption in 2030 as well as the prospective of China's electricity consumption and economic growth in the year 2050.