Neuroinflammation and Neurodegeneration
(Sprache: Englisch)
State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration). Many of the...
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Produktinformationen zu „Neuroinflammation and Neurodegeneration “
State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration). Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer's disease, Parkinson's disease, stroke, viral encephalitides and substance abuse. In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system. With rare exception, no or inadequate treatment exists for the diseases discussed in this book. An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters.
Klappentext zu „Neuroinflammation and Neurodegeneration “
State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration). Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer's disease, Parkinson's disease, stroke, viral encephalitides and substance abuse. In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system. With rare exception, no or inadequate treatment exists for the diseases discussed in this book. An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters.
State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases, and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration). Many of the diseases that are discussed in the book are of epidemic proportion, e.g., Alzheimer's disease, Parkinson's disease, stroke, viral encephalitides, and substance abuse. In addition to discussions of the involvement of neuroinflammation and neurodegeneration in these disorders, scientific reviews are presented on the cells and mediators that participate in defense of and damage to the nervous system. With rare exception, no or inadequate treatment exists for the diseases discussed in this book. An underlying premise of the book is that understanding of their shared pathogenic mechanisms will lead to improved therapies. Given the rapid evolution of the field of Neuroimmune Pharmacology, readers will find this book to be the most timely and authoritative reference on the subject of each of its chapters.
Inhaltsverzeichnis zu „Neuroinflammation and Neurodegeneration “
Part 1: Mechanisms of Brain Defense and NeuropathogenesisChapter 1: The Blood Brain Barrier
Victor Castro, Michal Toborek
Chapter 2: Immune Cell Trafficking in the Central Nervous System
Beena John, Christopher A. Hunter, Tajie H. Harris
Chapter 3: General Physiology and Pathophysiology of Microglia
Alexei Verkhratsky, Mami Noda
Chapter 4: Inflammation and the Pathophysiology of Astrocytes in Neurodegenerative Diseases
Gordon P. Meares, Etty N. Benveniste
Chapter 5: Oxidative stress, neuroinflammation, and neurodegeneration
Hui-Ming Gao, Hui Zhou, Jau-Shyong Hong
Chapter 6: Peripheral Neuroimmune Interactions and Neuropathic Pain
Halina Machelska
Part 2: Neurological Diseases and Inflammation
Chapter 7: Innate and Adaptive Immune-Mediated Neuroinflammation and Neurodegeneration in Parkinson's Disease
Rebecca A. Wilshusen, R. Lee Mosley
Chapter 8: Multiple sclerosis: impact on functioning of the blood-brain barrier
Mark R. Mizee, Gijs Kooij, Helga E. de Vries
Chapter 9: Neuroinflammation in Alzheimer's disease
Veronika M. Reinisch, Daniela L. Krause, Norbert Müller
Chapter 10: Neuroinflammation in Huntington's Disease
Roland G. W. Staal, Thomas Möller
Chapter 11: Neuroinflammation and immune regulation in ischemic stroke: identification of new pharmacological targets
Mario Di Napoli, Craig J. Smith, Stephen J. Hopkins, Aurel Popa-Wagner, Ana Maria Buga, Mark Slevic
Part 3: Infectious Diseases
Chapter 12: HIV/NeuroAIDS
Kelly Stauch, Howard S. Fox
Chapter 13: Herpes Simplex Virus Infections Of The Central Nervous System
Richard J. Whitley
Chapter 14: Congenital Cytomegalovirus Disease
Mark R. Schleiss
Chapter 15: Japanese Encephalitis: A Tale of Inflammation and Degeneration in the Central Nervous System
Kallol Dutta, Anirban Basu
Chapter 16: The biology and clinical consequence of infection with the human polyomavirus JCV
G. von Geldern, M. J. Barhams, E.O. Major
Chapter 17: Role of
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Retrovirus-Induced Transactivator Proteins in Neuroinflammatory Disease
Gregory Antell, Michael R. Nonnemacher, Vanessa Pirrone, Brian Wigdahl
Chapter 18: Immunopathogenesis of bacterial meningitis
Uwe Koedel, Matthias Klein, Hans-Walter Pfister
Chapter 19: Cerebral Malaria
Gregory S. Park, Chandy C. John
Part 4: Drugs of Abuse and NeuroAIDS
Chapter 20: HIV and Cocaine Interplay in HIV-associated Neurocognitive Disorders
Honghong Yao, Crstal Bethel-Brown, Shilpa Buch
Chapter 21: Methamphetamine Neurotoxicity and Neuroinflammatory Processes
Nicole A. Northrop, Bryan K. Yamamoto
Chapter 22: Drugs of Abuse and NeuroAIDS: Opiates
Thomas J. Rogers
Chapter 23: Cannabinoids
Paige S. Katz, Patricia E. Molina
Chapter 24: Alcohol and Neurodegeneration
Yuri Persidsky, Larisa Goffman, Raghava Potula
Part 5: Novel Approaches to Therapy
Chapter 25: Cell-Based Drug Delivery for Improving Antiretroviral Therapeutic Outcomes
JoEllyn M. McMillan, Howard E. Gendelman
Chapter 26: Immunomodulatory Therapeutics for Neurodegenerative Diseases
David J. Graber, William F. Hickey
Chapter 27: Therapeutic Potential Of Cannabinoids
Guy A. Cabral, Melissa Jamerson
Gregory Antell, Michael R. Nonnemacher, Vanessa Pirrone, Brian Wigdahl
Chapter 18: Immunopathogenesis of bacterial meningitis
Uwe Koedel, Matthias Klein, Hans-Walter Pfister
Chapter 19: Cerebral Malaria
Gregory S. Park, Chandy C. John
Part 4: Drugs of Abuse and NeuroAIDS
Chapter 20: HIV and Cocaine Interplay in HIV-associated Neurocognitive Disorders
Honghong Yao, Crstal Bethel-Brown, Shilpa Buch
Chapter 21: Methamphetamine Neurotoxicity and Neuroinflammatory Processes
Nicole A. Northrop, Bryan K. Yamamoto
Chapter 22: Drugs of Abuse and NeuroAIDS: Opiates
Thomas J. Rogers
Chapter 23: Cannabinoids
Paige S. Katz, Patricia E. Molina
Chapter 24: Alcohol and Neurodegeneration
Yuri Persidsky, Larisa Goffman, Raghava Potula
Part 5: Novel Approaches to Therapy
Chapter 25: Cell-Based Drug Delivery for Improving Antiretroviral Therapeutic Outcomes
JoEllyn M. McMillan, Howard E. Gendelman
Chapter 26: Immunomodulatory Therapeutics for Neurodegenerative Diseases
David J. Graber, William F. Hickey
Chapter 27: Therapeutic Potential Of Cannabinoids
Guy A. Cabral, Melissa Jamerson
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Bibliographische Angaben
- 2014, 2014, XVII, 600 Seiten, 35 farbige Abbildungen, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Phillip K. Peterson, Michal Toborek
- Verlag: Springer, Berlin
- ISBN-10: 1493910701
- ISBN-13: 9781493910700
- Erscheinungsdatum: 11.07.2014
Sprache:
Englisch
Pressezitat
"This is an outstanding text and atlas of neurodegenerative & neuroinflammatory diseases. ... This book is for cell biologists." (Joseph J. Grenier, Amazon.com, November, 2015)
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