Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome

I. EPIDEMIOLOGY AND OVERVIEW 1. Type 1 Diabetes Mellitus: An Overview SALEH ADI AND ANDREA GERARD GONZALEZ 2. Prediabetes: Prevalence, Pathogenesis, and Recognition of Enhanced Risk ALOK K. GUPTA, AJAY MENON, MEGHAN BRASHEAR AND WILLIAM D. JOHNSON 3. Targeting Prediabetes to Preempt Diabetes SREEDHARAN N, MAHADEV RAO AND SONAL SEKHAR M 4. Obesity and Type 2 Diabetes in Youths: New Challenges to Overcome NICOLA SANTORO, COSIMO GIANNINI AND SONIA CAPRIO 5. Roles of Environmental Pollution and Pesticides in Diabetes and Obesity: The Epidemiological Evidence CHARLES J. EVERETT, DANIRA MEDUNJANIN AND IVAR L. FRITHSEN 6. An Overview of the Roles of the Gut Microbiome in Obesity and Diabetes GILLIAN M. BARLOW, EUGENIA A. LIN AND RUCHI MATHUR

II. TYPES OF DIABETES AND ITS CORRELATION WITH OTHER DISEASES 7. Role of Peripheral Neuropathy in the Development of Foot Ulceration and Impaired Wound Healing in Diabetes Mellitus FRANCESCO TECILAZICH AND ARISTIDIS VEVES 8. The Association of Diabetes in the Onset of Dementia in the Elderly Population: An Overview ABHAI KUMAR AND SMITA SINGH 9. The Role of Insulin Resistance in the Cardiorenal Syndrome ADAM WHALEY-CONNELL AND JAMES R. SOWERS 10. An Overview on Diabetic Nephropathy KEI FUKAMI AND SHO-ICHI YAMAGISHI 11. An Overview of Diabetic Retinopathy SHINTARO NAKAO, SHIGEO YOSHIDA AND KOH-HEI SONODA 12. An Overview of Gestational Diabetes CHRISTOPHER FEDERICO AND GABRIELLA PRIDJIAN 13. Diabetes, a Potential Threat to the Development and Progression of Tumor Cells in Individuals SAYANTAN MAITRA, STABAK DAS AND PRADIPTA BANERJEE

III. MOLECULAR INSIGHTS OF DIABETES AND METABOLIC SYNDROME 14. Lipid-Induced Insulin Resistance: Molecular Mechanisms and Clinical Implications SATINATH MUKHOPADHYAY, DEEP DUTTA AND DIPYAMAN GANGULY 15. Gene-Environment Interaction in the Pathogenesis of Type 2 Diabetes KIAN-PENG GOH 16. Renal Sodium-Glucose Transporter-2 Inhibitors and Antidiabetic Agents ANAND S.

Debasis Bagchi, PhD, MACN, CNS, MAIChE, received his Ph.D. in Medicinal Chemistry in 1982. He is a Professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy, Houston, TX, and Chief Scientific Officer at Cepham Research Center, Piscataway, NJ, Adjunct Faculty in Texas Southern University, Houston, TX. He served as the Senior Vice President of Research & Development of InterHealth Nutraceuticals Inc, Benicia, CA, from 1998 until Feb 2011, and then as Director of Innovation and Clinical Affairs, of Iovate Health Sciences, Oakville, ON, until June 2013. Dr. Bagchi received the Master of American College of Nutrition Award in October 2010. He is the Past Chairman of International Society of Nutraceuticals and Functional Foods (ISNFF), Past President of American College of Nutrition, Clearwater, FL, and Past Chair of the Nutraceuticals and Functional Foods Division of Institute of Food Technologists (IFT), Chicago, IL. He is serving as a Distinguished Advisor on the Japanese Institute for Health Food Standards (JIHFS), Tokyo, Japan. Dr. Bagchi is a Member of the Study Section and Peer Review Committee of the National Institutes of Health (NIH), Bethesda, MD. He has published 321 papers in peer reviewed journals, 30 books, and 18 patents. Dr. Bagchi is also a Member of the Society of Toxicology, Member of the New York Academy of Sciences, Fellow of the Nutrition Research Academy, and Member of the TCE stakeholder Committee of the Wright Patterson Air Force Base, OH. He is also Associate Editor for the Journal of Functional Foods, Journal of the American College of Nutrition, and the Archives of Medical and Biomedical Research, and is also serving as Editorial Board Member of numerous peer reviewed journals, including Antioxidants & Redox Signaling, Cancer Letters, Toxicology Mechanisms and Methods, and The Original Internist, among others. Dr. Sreejayan Nair is a Professor of Pharmacology and the