Post-Transcriptional Gene Regulation

The Role of Co-transcriptional Recruitment of RNA Binding Proteins in the Maintenance of Genomic Stability (Jennifer A. Aoki and James L. Manley)Transcription Termination by RNA Polymerase II (Minkyu Kim and Stephen Buratowski)Posttranscriptional Gene Regulation by an Editor: ADAR and its Role in RNA Editing (Louis Valente Yukio Kawahara, Boris Zinshteyn, Hisashi Iizasa and Kazuko Nishikura)Posttranslational Modification of Sm Proteins: Diverse Roles in sn RNP Assembly and Germ Line Specification (Graydon B. Gonsalvez and A. Gregory Matera)Structure, Function, and Biogenesis of Small Nucleolar Ribonucleoparticles (Katherine S. Godin and Gabriele Varani)Mechanistic Insights into Mammalian pre-mRNA Splicing (Sebastian M. Fica, Eliza C. Small, Melissa Mefford, and Jonathan P. Staley)Splicing Decisions Shape Neuronal Protein Function Across the Transcriptome (Jill A. Dembowski and Paula J. Grabowski)Noncoding RNA: The Major Output of Gene Expression (Matthias Harbers and Piero Carninci)Noncoding RNAs, Neurodevelopment and Neurodegeneration (Mengmeng Chen, Jianwen Deng, Mengxue Yang, Kun Zhu, Jianghong Liu, Li Zhu, and Jane Y. Wu)The Evolution of the Modern RNA World (Ying Chen, Hongzheng Dai and Manyuan Long)

Dr. Jane Y. Wu is the Charles Louis Mix Professor in Neurology at Lurie Cancer Center and the Center for Genetic Medicine of Northwestern University in Chicago, USA. Having obtained her degree from Stanford Univeristy and postdoctoral training at Harvard University, Dr. Wu has been studying molecular mechanisms underlying pre-mRNA splicing and neurodevelopment/degeneration, both linking basic biology to human diseases.