Postural Tachycardia Syndrome

Section 1 - Pots, an introduction.-  Chapter 1. Introduction.- Chapter 2. Historical background.- Chapter 3. Clinical presentation.- Section 2 - Specialty assessment.- Chapter 4. Diagnostic Criteria for Postural Tachycardia Syndrome: consideration of the clinical features differentiating POTS from other disorders of orthostatic intolerance.- Chapter 5. Pathophysiology and classification of PoTS.- Chapter 6. Cardiological considerations: tests to consider, are they useful and what do they show?.- Chapter  7. Neurological Investigations.- Chapter 8. Autonomic Testing: Autonomic testing: Active Stand and Tilt Table Test.- Chapter 9.  Additional autonomic tests.- Chapter 10. Cardiovascular Red Flag symptoms in PoTS.- Chapter 11.  Neurological red flags in common neurological conditions associated with PoTS.- Section 3 - Associated conditions.- Chapter 12. Rheumatology in Postural Tachycardia Syndrome.- Chapter 13.  Headache in postural tachycardia syndrome.- Chapter 14. Postural Tachycardia Syndrome and Sleep.- Chapter 15. Investigations of Endocrinopathies.- Chapter 16. Postural Tachycardia Syndrome and the Gut.- Chapter 17. Urological considerations.- Chapter 18. Gynaecological considerations.- Chapter 19.  Dizziness - the audiovestibular perspective.- Section 4 - Potential linked conditions.- Chapter 20. Is PoTS an autoimmune condition?.- Chapter 21. Mast cell activation syndrome (MCAS).- Chapter 22. Inherited Metabolic Diseases.- Chapter 23. Chronic Fatigue Syndrome.- Chapter 24. Lyme disease.- Section 5 - Therapy.- Chapter 25. Non-pharmacological management (hydration, diet and compression).- Chapter 26. Exercise Guidelines for Postural Tachycardia Syndrome.- Chapter 27. Medication in PoTS; an overview.- Chapter 28. Midodrine.-Chapter 29. Ivabradine.- Chapter 30. Beta blockers.- Chapter 31. Fludrocortisone.- Chapter 32. Octreotide.- Chapter 33. Clonidine.- Chapter 34. Other medications: Desmopressin, Pyridostigmine Erythropoietin and

Dr Nicholas Gall qualified in 1993 from Guy's and St Thomas' Hospitals. He trained in General Internal Medicine and Cardiology and is a Consultant Cardiologist (electrophysiology) at King's College Hospital and an Honorary Senior Lecturer at King's College. He has a particular interest in loss of consciousness and autonomic conditions including PoTS: Neuro-cardiology. He has published widely, has an active PoTS research program and speaks at National and International conferences. With Prof Kavi, he developed the PoTS masterclass and has run the London Syncope conference since 2010. He is a Patron of PoTS-UK and medical adviser to STARS.

Dr Lesley Kavi obtained her medical degree at Glasgow University. She is currently working as a GP in Solihull and is Visiting Professor at Birmingham City University where she teaches on the Advanced Practice MSc. She was appointed as RCGP Syncope Clinical Champion in 2019 and developed an online open access toolkit for use by clinicians in primary care. In 2011 Lesley became a trustee of PoTS UK, the national charity that supports patients with postural tachycardia syndrome. In 2017 she took on the role of chairperson. Her special interests include PoTS, syncope and women's health.

Dr Melvin Lobo is a Consultant Cardiovascular Physician and Director of the Bart's Blood Pressure Clinic based in the Barts Heart Centre and the William Harvey Research Institute. He has a specialist interest in blood pressure disorders of all types, PoTS and autonomic control of the circulation. He is an accredited Clinical Hypertension Specialist of the European Society of Hypertension (ESH) and British Hypertension Society. Professor Lobo has participated in numerous clinical trials, particularly in the field of novel device therapy of hypertension. His research work has been featured on television and in the national press on numerous occasions.