Prevention of Nausea and Vomiting in Cancer Patients

Introduction.- Pathophysiology and classification of chemotherapy-induced nausea and vomiting.- Risk factors associated with nausea and vomiting after chemotherapy.- Risk factors associated with nausea and vomiting after radiotherapy.- Antiemetic drugs.- Antiemetic prophylaxis of chemotherapy-induced nausea and vomiting.- Antiemetic prophylaxis of radiotherapy-induced nausea and vomiting.- Summary of the approach to treatment of chemotherapy-induced nausea and vomiting.- Conclusions and future directions.

Matti Aapro, MD received his medical degree from the Faculty of Medicine, University of Geneva, Switzerland. He was subsequently a fellow at the Arizona Cancer Center in Tucson, USA, and later was the founding chair of the Medical and Radiation Therapy Department at the European Institute of Oncology in Milan, Italy. He is presently the dean of the Multidisciplinary Oncology Institute,Genolier, Switzerland. Dr Aapro serves as Executive Director of the International Society for Geriatric Oncology. He was a member of the Board of the European Organization for Research and Treatment of Cancer. Dr Aapro is a board member and a past-president of the Multinational Association for Supportive Care in Cancer (MASCC). Dr Aapro chaired the scientific and organizing committees of the International Union Against Cancer (UICC) World Cancer Congress (WCC) of 2008 and continues to serve UICC for the WCC in China in 2010. He is a member of the European Cancer Organisation/European Society of Medical Oncology (ECCO/ESMO) 2011 Scientific Committee. He coordinates the Sharing Progress in Cancer Care program of the European School of Oncology. Dr Aapro is the editor-in-chief of Critical Reviews in Oncology/Hematology, as well as the associate editor of Annals of Oncology, the associate editor for the geriatric section of The Oncologist and member of the editorial board of Journal of Clinical Oncology (breast section). He has authored more than 300 publications and his major interests are new drug development, breast cancer, cancer in the elderly, and supportive care. Karin Jordan, MD, PhD graduated from Martin Luther University of Halle-Wittenberg, Germany, after internships in the bone-marrow transplantation program at the University of California, San Diego, USA, and in general surgery at the University of Newcastle, UK. Following a number of posts at the University Hospital, Halle, and Bernward Hospital, Hildesheim, Germany, she was appointed as a specialist in internal medicine in

From the reviews:



"This quick reference guide to preventing nausea and vomiting in cancer patients describes the antiemetic drugs and their actions and provides recommendations with different chemotherapies and radiation therapy. ... It is written for anyone who desires more knowledge about the prevention or control of CINV. ... this book provides helpful, succinct information for healthcare professionals caring for cancer patients." (Celeste Taylor-Ryman, Doody's Book Reviews, February, 2014)