Redox Signaling and Regulation in Biology and Medicine
(Sprache: Englisch)
This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox processes,...
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Klappentext zu „Redox Signaling and Regulation in Biology and Medicine “
This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox processes, demonstrating that complex science can be presented in a clear and almost entertaining way.Perfect for students and junior researchers, this is an equally valuable addition to courses in biochemistry, molecular biology, cell biology, and human physiology.
Inhaltsverzeichnis zu „Redox Signaling and Regulation in Biology and Medicine “
INTRODUCTIONThe intracellular redox equilibrium
Causes of oxidative stress
Biological redox systems
REDOX CONTROL
The chemical basis of biological redox control
Simple cellular redox responses
Redox-modulation of protein activity: redox switches, catalysis, chaperones
REDOX SIGNALLING
Protein-based signalling pathways
Redox-controlled transcription factors and gene expression
Nitric oxide in redox signalling
nox/duox signalling
Metal ions in redox control
REDOX CONTROL IN HEALTH AND DISEASE
Apoptosis and other cellular events
Imflammatory diseases
Neurodegenerative diseases
Cancer
Oxidative stress and ageing
Autoren-Porträt
Claus Jacob is the head of the department of Bioinorganic Chemistry at Saarland University (Germany). Professor Jacob studied Chemistry at the Universities of Leicester and Oxford (UK) and received his PhD in bioinorganic chemistry from Oxford University in 1997. Since then, he has also been researching and lecturing at the Heinrich Heine Universität in Düsseldorf (Germany), the University of Exeter (UK) and the University of Metz (France).Paul Winyard is a Professor of Experimental Medicine at the Universities of Exeter and Plymouth (UK). After his studies in Biochemistry at the Universities of Gothenburg (Sweden) and Wales (UK), he obtained his PhD in Medicine from the University of Birmingham (UK) in 1987. Between 1988 and 2001 he was Lecturer and Reader at Queen Mary University (London) and the London Hospital Medical College. He also spent one year as a visiting Professor at the University of California in San Francisco (USA).
Bibliographische Angaben
- 2009, 1. Auflage, XXXIII, 481 Seiten, 7 farbige Abbildungen, 60 Schwarz-Weiß-Abbildungen, Maße: 18,2 x 24,7 cm, Gebunden, Englisch
- Herausgegeben: Claus Jacob, Paul G. Winyard
- Verlag: Wiley-VCH
- ISBN-10: 3527319255
- ISBN-13: 9783527319251
- Erscheinungsdatum: 22.04.2009
Sprache:
Englisch
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