Rheumatoid Arthritis and Proteus

Scope and Distribution of the RA Problem.- History of the Attempts to Find the Cause of RA.- HLA-DR1/4 and Antibodies to Proteus in London.- Antibodies to Proteus in Irish patients with rheumatoid arthritis.- Antibodies to Proteus in rheumatoid arthritis patients from Bermuda and from Hertfordshire in England.- Antibodies to Proteus in rheumatoid arthritis patients from Brest and Toulouse in France.- Dutch patients with rheumatoid arthritis have antibodies to Proteus.- Anti-Proteus antibodies in Norwegian rheumatoid arthritis patients following a lactovegetarian diet.- Antibodies to Proteus in rheumatoid arthritis patients from Norway, Spain and England.- Antibodies to Proteus in rheumatoid arthritis patients from southern Japan.- Urine Cultures and Correlation.- Molecular similarity between the "shared epitope" of rheumatoid arthritis and bacteria.- The "shared epitope", Proteus haemolysin, XI collagen and rheumatoid arthritis.- Gram-negative bacteria possess sequences which resemble the "shared epitope"but only Proteus infect rheumatoid arthritis patients.- Immune responses to Proteus in rheumatoid arthritis patients from Finland and Japan.- Molecular similarity between the rheumatoid arthritis associated motif EQKRAA and structurally related sequences of Proteus.- Rheumatoid arthritis sera are cytotoxic to cells bearing HLA and collagen susceptibility sequences.- The scientific method of Sir Karl Popper. Rheumatoid arthritis and "Popper sequences".

From the reviews:"This book explores the idea that rheumatoid arthritis (RA) is caused by a urinary tract infection as a result of Proteus bacteria. ... Medical students, rheumatology fellows, rheumatologists, and scientists will benefit from this book ... . This is an easy-to-read and informative book, with good charts and tables, on the relationship between Proteus bacteria and RA." (Richa Gupta, Doody's Review Service, April, 2012)